Ohio State at Iowa Best Pick, Prediction and Odds

No. 7 Ohio State visits No. 17 Iowa on Saturday 3 October, at Kinnick Stadium in Iowa City, with kickoff at 3:30 PM ET. Ohio State opened as a 14-point favorite. Rankings are from the AP poll for week 4.

This is the early page for the game: what is already known. Our full prediction, with the call and the numbers behind it, goes up on this page before kickoff.

The two teams in 2026, through 23 September

Ohio State is 2-1 this season. Most recently it beat Kent State 59-3 at home on 19 September. It has scored 46.0 points a game and allowed 10.0.

Iowa is 3-0 this season. Most recently it beat Northern Iowa 55-0 at home on 19 September. It has scored 37.0 points a game and allowed 4.3.

Last season

Ohio State went 12-2 in 2025, scoring 33.4 points a game and allowing 9.3. Its season ended with a loss against Miami, 24-14.

Iowa went 9-4 in 2025, scoring 29.3 points a game and allowing 16.1. Its season ended with a win against Vanderbilt, 34-27.

The early line

At DraftKings, read 24 September 2026, Iowa is +14. The total is 44.5. The moneylines price Iowa to win 16.0% of the time, with the margin removed.

Lines move through the week. The full prediction reads them again on the day it goes up.

The teams

The Ohio State Buckeyes and Iowa Hawkeyes team pages hold both schedules and last season’s results. Every game this week is on our college football predictions page.

Ohio State at Iowa, Saturday 3 October, 3:30 PM ET, at Kinnick Stadium in Iowa City. Results: ESPN, read 24 September 2026. Line: DraftKings via ESPN, read 2026-09-24 05:06 UTC. Rankings: 2026 NCAA Football Rankings – AP Poll Week 4.