Our number has Penn State by 9.4. At -1.5, take Penn State.

USC Trojans
Upcoming games
The Trojans covered the spread in one of five road games in 2025, a rate only six FBS teams fell below. USC football went 9-3 straight up and 5-7 against the line, and won four of five November games while covering one.
Home and away
USC was 7-0 at home in the 2025 regular season and 2-3 away. Against the spread it was 4-3 at home and 1-4 on the road. That 20% road cover rate had six FBS teams beneath it and seven alongside. The one road cover was a 34-24 loss at Notre Dame getting 10.5.
On the moneyline the five priced home games made 1.37 units and the five priced road games lost 2.37.
Big spreads
The Trojans laid 14.5 points or more six times and covered three: 73-13 over Missouri State, 59-20 over Georgia Southern and 38-17 over Northwestern. The other three were wins that fell short of the line: 33-17 at Purdue at -20.5, 45-31 over Michigan State at -18.5 and 29-10 over UCLA at -21.5. Overall as favorites they were 9-1 and 4-6; the loss was 34-32 at Illinois at -240.
November
November went 4-1 straight up and 1-4 against the spread. Narrow wins over Nebraska (21-17 at -4.5) and Iowa (26-21 at -6.5) missed, as did the 42-27 loss at Oregon getting 12.5.
Moneyline and total
Ten games had a price posted; a unit on USC in each lost 1.01. The eight as favorites made 0.99, and the two as underdogs, at Notre Dame (+300) and Oregon (+340), lost both units. The Trojans scored 36.5 a game, behind only 12 FBS teams, and the totals split six over, six under.
USC lost the Alamo Bowl 30-27 to TCU.
Questions and answers
How does USC do against the spread on the road?
1-4 in 2025; six FBS teams had a lower road cover rate.
Is USC good at home?
7-0 straight up and 4-3 against the spread in 2025.
How did USC do in November 2025?
Four wins in five games but only one cover.
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