Notre Dame at North Carolina Best Pick, Prediction and Odds

No. 3 Notre Dame visits North Carolina on Saturday 3 October, at Kenan Stadium in Chapel Hill, with kickoff at 12:00 AM ET. Notre Dame is a 20.5-point favorite. Rankings are from the AP poll for week 4.

This is the early page for the game: what is already known. Our full prediction, with the call and the numbers behind it, goes up on this page before kickoff.

The two teams in 2026, through 23 September

Notre Dame is 3-0 this season. Most recently it beat Michigan State 27-10 at home on 19 September. It has scored 40.0 points a game and allowed 7.7.

North Carolina is 2-1 this season, 0-1 in the Atlantic Coast Conference. Most recently it lost to Clemson 28-20 on the road on 19 September. It has scored 23.3 points a game and allowed 13.7.

Last season

Notre Dame went 10-2 in 2025, scoring 42.0 points a game and allowing 17.6.

North Carolina went 4-8 in 2025, scoring 19.2 points a game and allowing 24.5.

The early line

At DraftKings, read 24 September 2026, North Carolina is +20.5 after opening at +24.5. The total is 49.5. The moneylines price North Carolina to win 9.6% of the time, with the margin removed.

Lines move through the week. The full prediction reads them again on the day it goes up.

The teams

The Notre Dame Fighting Irish and North Carolina Tar Heels team pages hold both schedules and last season’s results. Every game this week is on our college football predictions page.

Notre Dame at North Carolina, Saturday 3 October, 12:00 AM ET, at Kenan Stadium in Chapel Hill. Results: ESPN, read 24 September 2026. Line: DraftKings via ESPN, read 2026-09-24 05:06 UTC. Rankings: 2026 NCAA Football Rankings – AP Poll Week 4.