San Diego State at Toledo Best Pick, Prediction and Odds

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Our number has Toledo by 15.5. At -3, take Toledo.

Toledo is a 3-point favourite over San Diego State at DraftKings. It opened as a 1.5-point underdog. Our number is Toledo by 15.5. The gap is 12.5 points, and the threshold for a bet here is 3.

How the number is built

The method is one clause: our number is half the difference between the home team’s average margin at home and the visitor’s average margin on the road, against FBS teams only, 2025 and 2026 together.

Toledo is 6-0 at home against FBS teams over that span, winning by 28.3 points a game across 6 games. San Diego State is 3-4 on the road against FBS teams, losing by 2.7 a game across 7 games. The difference is 31.0 points. Half of it is 15.5.

Six and seven games is thin. Two of the thirteen are from 2026: Toledo’s 49-48 home win over Temple on 19 September, and San Diego State’s 28-10 loss at UCLA on 12 September.

Toledo at home

The home sample carries the number. In 2025 Toledo beat Western Kentucky 45-21, Akron 45-3, Kent State 45-10, Northern Illinois 42-3 and Ball State 38-9 at home. The one close game is this season’s 49-48 over Temple.

Take the largest win, 45-3 over Akron, out of the sample. Toledo’s home average is then 25.6 across 5 games. Add San Diego State’s 2.7 and halve it: Toledo by 14.15. The side holds with room to spare.

San Diego State’s road games split. It won 6-3 at Northern Illinois, 44-10 at Nevada and 23-0 at Fresno State in 2025. It lost 36-13 at Washington State, 38-6 at Hawai’i and 23-17 at New Mexico, then 28-10 at UCLA this season.

2026 so far

Toledo is 2-1. It lost 30-20 at Michigan State on 4 September, beat Central Connecticut, a team outside the FBS, 63-10, and then beat Temple by a point. Against its two FBS opponents it has scored 34.5 a game and allowed 39.0.

2026 point margin in every game, Toledo and San Diego State2026: point margin in every game so farToledo2-1, +14.7 a game-10Michigan State+53Central Connecticut+1TempleSan Diego State1-2, +0.7 a game+33Portland State-18UCLA-13James MadisonColoured bars are wins, dark grey losses, light grey games against teams outside the FBS.
Source: ESPN results, read 23 September 2026; every 2026 final checked against Nucleus where Nucleus holds the game.

San Diego State is 1-2. It beat Portland State, a team outside the FBS, 53-20, lost at UCLA, and lost 26-13 at home to James Madison on 19 September. Against its two FBS opponents it has scored 11.5 a game.

This is not a conference game. San Diego State plays in the Pac-12 and Toledo in the Mid-American.

Last season

San Diego State went 9-4 in 2025 and won by 11.0 points a game. Its season ended with a 49-47 loss to North Texas at a neutral site on 27 December. Toledo went 8-5 and won by 17.5 a game.

2025 point margin in every game, Toledo and San Diego State2025: point margin in every game, bowls and playoffs includedToledo8-5, +17.5 a game-8+24+60-1+42-5+35-21+39+21+29+18-5San Diego State9-4, +11.0 a game+42-23+34+3+21+34+23+17-32+10+22-6-2Oldest game on the left. Light grey bars are games against teams outside the FBS.
Source: ESPN results, read 23 September 2026.

Toledo’s 2025 ended with a 27-22 loss to Louisville at a neutral site on 23 December. It was 6-0 at home that season. The two teams did not meet in 2025, and have not met this season.

The price

Toledo opened at +1.5 and is -3 now, read 24 September 2026 at 04:28 UTC at DraftKings via ESPN. That is a 4.5-point move toward Toledo. Both sides of the spread are priced at -110.

Toledo opened +1.5 and is -3 nowToledo's line, from the open to nowpickopen +1.5now -3Negative numbers mean Toledo is giving points. The line has moved 4.5 points toward Toledo.
Prices: DraftKings via ESPN, read 2026-09-24 04:28 UTC.

The moneyline has Toledo at -148 and San Diego State at +124. At the open it was Toledo -102 and San Diego State -118. With the margin removed, the current price has Toledo winning 57.2% of the time. ESPN’s FPI has Toledo at 66.1%.

Moneyline implies San Diego State 42.8 percent, Toledo 57.2 percentChance to win the game, as pricedSan Diego State 42.8%Toledo 57.2%From DraftKings's moneylines, San Diego State +124 and Toledo -148, margin removed.
Source: DraftKings via ESPN, read 2026-09-24 04:28 UTC.

The market has already moved our way by 4.5 points. It is still 12.5 short of our number.

Pick: Toledo -3

Toledo -3 at -110. The gap is 12.5 points against a 3-point threshold.

It rests on 13 games, split 6 and 7, and 11 of them are from 2025. The size of the gap is mostly the size of Toledo’s 2025 home wins.

What changes it

A line move toward Toledo. At Toledo -12.5 the gap is 3.0 and the bet stands. At -13 it is 2.5, and the call becomes a pass.

Availability is the other thing, and this page does not state it. Check the injury report before you bet.

The total

The total opened at 48.5 and is 51.5 now, over -115 and under -105, as read at DraftKings. That is a 3-point rise.

Game totals for Toledo and San Diego State against 51.5Total points in every game against FBS teams, 2025 and 2026, against this game's 51.5010203040506070809010051.5Toledo3 of 14 over 51.5San Diego State3 of 14 over 51.5Each dot is one game against an FBS team. Dots stack where games had the same total.
Source: ESPN results, read 23 September 2026; every 2026 final checked against Nucleus where Nucleus holds the game. The line: DraftKings via ESPN, read 2026-09-24 04:28 UTC.

Against FBS teams across 2025 and 2026, San Diego State’s games went over 51.5 in 3 of 14, and Toledo’s in 3 of 14. San Diego State’s two FBS games this season produced 38 and 39 points. Toledo’s produced 50 and 97.

Lean under 51.5. Both samples sit under it about four times in five, and the 3-point rise since the open gives the under more room.


San Diego State at Toledo, Saturday 26 September, 12:00 PM ET, Glass Bowl, Toledo. Prices: DraftKings via ESPN, read 24 September 2026, 04:28 UTC. Results: ESPN, read 23-24 September 2026. Neither team is ranked in the AP Poll, Week 4, 2026. Nothing here states who is available.