New York Giants vs Minnesota Vikings Picks and Predictions December 21st 2025

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Game Preview New York Giants @ Minnesota Vikings

The New York Giants visit the Minnesota Vikings in a Week 16 NFC matchup with postseason implications for Minnesota and little but pride on the line for New York. The Vikings are pushing for a Wild Card berth, while the Giants continue evaluating their young core and planning for the offseason.

Minnesota has dominated recent home performances, while the Giants have struggled to consistently move the ball against playoff-caliber defenses. Bettors should weigh motivation, injuries, and quarterback play in what projects to be a slow-paced, defense-heavy contest.

Find the latest line movement and player updates at the NFL scores and odds board.

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Odds and Key Information

  • Spread: Vikings -6.5
  • Total: 39.5
  • Moneyline: Giants +230, Vikings -280
  • Kickoff: 1:00 PM ET
  • Venue: U.S. Bank Stadium, Minneapolis, MN

The Vikings opened as 6.5-point favorites, and early money has backed them at home. The total is low, reflecting expectations of a defense-first game. View full market analysis on the NFL betting guide.

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New York Giants Outlook

The New York Giants are 5-9 and out of the playoff race. Third-string quarterback Tommy DeVito remains the starter, and while his mobility adds a dimension to the offense, the passing attack ranks near the bottom of the league in yards per attempt.

Saquon Barkley continues to be the team’s offensive engine, averaging 4.6 yards per carry with multiple explosive plays over 20 yards. Still, the offensive line remains a liability, and the Giants struggle on third downs and in the red zone.

Defensively, New York has limited rushing efficiency but struggles in coverage, allowing a completion rate over 68% to opposing quarterbacks. Their betting trends and weekly matchup data are updated on the NFL picks page.

Minnesota Vikings Outlook

The Minnesota Vikings sit at 8-6 and currently hold an NFC Wild Card spot. Quarterback Joshua Dobbs continues to manage the offense, aided by elite talent like Justin Jefferson and T.J. Hockenson. The Vikings rank top-10 in red zone scoring and average over 24 points per game at home.

Defensively, Minnesota has been one of the league’s most improved units. Their blitz rate has increased under DC Brian Flores, and they rank top five in QB pressure rate. The secondary, anchored by Byron Murphy Jr., has held opponents under 200 passing yards in four of their last six games.

Minnesota is 5-2 ATS at home this season and has won seven straight against teams with losing records. You can follow their playoff journey in the NFL postseason outlook.

Key Matchup Table

Key MatchupEdge
Quarterback PlayVikings
Run GameGiants
Defensive PressureVikings
Red Zone OffenseVikings
Coaching AdjustmentsVikings

The New York Giants are 3-6 ATS in their last nine games and 1-4 ATS in their last five road appearances. The under has cashed in six of their last eight games overall.

The Minnesota Vikings are 4-1 ATS in their last five home games and 6-2 ATS when facing teams with a losing record. They’ve also hit the under in four of their last six.

For more detailed totals insights and sharp betting signals, check out our NFL Week 16 odds and predictions.

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Prediction

The Vikings are in a must-win scenario and have the advantage at every major offensive and defensive position. The Giants will try to shorten the game with Barkley, but unless they can force multiple turnovers, it’s difficult to see them keeping pace for four quarters.

Expect a conservative script from Minnesota early, followed by more downfield plays if they establish control by halftime. This game projects as a comfortable Vikings win with a lean toward the under based on both teams’ recent scoring patterns.

Projected Score: Vikings 23, Giants 13
Spread Pick: Vikings -6.5
Total Lean: Under 39.5

More game breakdowns are featured in our Sunday Night Football odds preview.

Why You Need Expert Picks

With motivation, quarterback play, and situational trends all in play, games like Giants vs Vikings require more than basic stat-checking. Our NFL picks section provides expert betting advice with sides, totals, and props.

Follow the Handicappers Leaderboard to see which cappers are outperforming the market. For added betting angles, explore NFL underdogs, MVP odds, and parlay strategies.

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