The Jacksonville Jaguars are the AFC South favorite at -380 on DraftKings, as ESPN listed the market on October 14, 2026. The Houston Texans are +600, the Indianapolis Colts +650 and the Tennessee Titans +15000.
Jacksonville is 4-1, two games ahead of Indianapolis at 2-3. Houston is 1-4 and Tennessee is 0-5. The Jaguars have built that lead without playing a division game, and their first is against Houston on October 18.
AFC South odds
| Team | Price | Implied chance | Share with the margin removed | Record |
|---|---|---|---|---|
| Jacksonville Jaguars | -380 | 79.2% | 73.7% | 4-1 |
| Houston Texans | +600 | 14.3% | 13.3% | 1-4 |
| Indianapolis Colts | +650 | 13.3% | 12.4% | 2-3 |
| Tennessee Titans | +15000 | 0.7% | 0.6% | 0-5 |
DraftKings’ market on the AFC South winner, taken from ESPN at 21:42 UTC on October 14, 2026. Records are from ESPN’s standings.
At -380 a bettor puts up $380 to win $100. The bet only breaks even if Jacksonville wins the division 380 times in 480, which is 79.2%. For the plus prices the sum is 100 over the price plus 100: 14.3% for the Texans at +600 and 13.3% for the Colts at +650. Houston, at 1-4, is priced shorter than Indianapolis at 2-3.
Those four rates make 107.4% between them. The 7.4 points past 100 are the book’s margin, and with it removed the market has Jacksonville at 73.7%, Houston at 13.3%, Indianapolis at 12.4% and Tennessee at 0.6%.
This page takes no side in the AFC South market. A price is worth a bet when your own estimate of a team’s chance is higher than the rate it needs, and at -380 that bar is close to four in five. Our futures bet guide shows how the payout is worked out.
AFC South standings
| Team | Record | Division | Conference | Points for | Points against | Difference | Games behind |
|---|---|---|---|---|---|---|---|
| Jacksonville Jaguars | 4-1 | 0-0 | 3-1 | 123 | 70 | +53 | – |
| Indianapolis Colts | 2-3 | 1-0 | 1-3 | 124 | 138 | -14 | 2 |
| Houston Texans | 1-4 | 1-1 | 1-3 | 110 | 112 | -2 | 3 |
| Tennessee Titans | 0-5 | 0-1 | 0-3 | 58 | 109 | -51 | 4 |
ESPN’s standings after Week 5, which ended on Monday, October 12, five games into each team’s season.
Jacksonville has allowed 70 points, 39 fewer than any other team in the division, and has outscored its opponents by 53. Tennessee has scored 58 points in five games. Houston is 1-4 with a point difference of minus two.
Next game for each AFC South team
| Game | Kickoff | Spread | Moneyline | Total | Our page |
|---|---|---|---|---|---|
| Texans at Jaguars (neutral site: London, England) | Sun, October 18, 9:30 am ET | Jaguars -2.5 (-115), Texans +2.5 (-105) | Jaguars -142, Texans +120 | Over 42.5 (-112), Under 42.5 (-108) | |
| Titans at Colts | Sun, October 18, 1:00 pm ET | Colts -7 (-105), Titans +7 (-115) | Colts -340, Titans +270 | Over 43.5 (-118), Under 43.5 (-102) | Titans at Colts prediction |
DraftKings lines from ESPN at 21:42 UTC on October 14, 2026.
All four teams play a division game on October 18. Texans at Jaguars is at a neutral site in London, with Jacksonville the designated home team. The Jaguars then have their bye in Week 7.
AFC South division games left
| Week | Game | Kickoff |
|---|---|---|
| 6 | Texans at Jaguars (neutral site: London, England) | Sun, October 18, 9:30 am ET |
| 6 | Titans at Colts | Sun, October 18, 1:00 pm ET |
| 8 | Colts at Jaguars | Sun, November 1, 1:00 pm ET |
| 10 | Jaguars at Titans | Sun, November 15, 1:00 pm ET |
| 11 | Colts at Texans | Thu, November 19, 8:15 pm ET |
| 12 | Titans at Jaguars | Sun, November 29, 4:05 pm ET |
| 15 | Jaguars at Texans | Sun, December 20, 1:00 pm ET |
| 15 | Colts at Titans | Sun, December 20, 1:00 pm ET |
| 18 | Jaguars at Colts | January 10, time not set |
| 18 | Titans at Texans | January 10, time not set |
The two Week 18 games are dated on ESPN’s schedule with no kickoff time.
Ten of the 12 division games remain, and Jacksonville plays in six of them. Indianapolis and Tennessee have five left each and Houston has four.
The Colts play the Jaguars on November 1 in Jacksonville and in Week 18 in Indianapolis. Houston’s two games with Jacksonville are the London game and a home game on December 20.
The two division games played so far both involved Houston:
| Week | Date | Game | Result |
|---|---|---|---|
| 3 | September 27 | Texans at Colts | Colts 19, Texans 17 |
| 5 | October 11 | Texans at Titans | Texans 26, Titans 3 |
What each AFC South price needs
Jacksonville, -380. The Jaguars have to win the division 79.2% of the time for the price to break even. Their two-game lead comes entirely from games outside the division.
Houston, +600. $100 wins $600 and needs 14.3%. The Texans are three games back at 1-4, and their one win was 26-3 at Tennessee on October 11.
Indianapolis, +650. $100 wins $650 and needs 13.3%. The Colts are the only team with a division win and no division loss, 19-17 over Houston on September 27, and they have allowed 138 points, the most of the four.
Tennessee, +15000. $100 wins $15,000 and needs 0.7%. The Titans are four games behind after five.
The AFC South last season
| Team | Record | Division | Points for | Points against |
|---|---|---|---|---|
| Jacksonville Jaguars | 13-4 | 5-1 | 474 | 336 |
| Houston Texans | 12-5 | 5-1 | 404 | 295 |
| Indianapolis Colts | 8-9 | 2-4 | 466 | 412 |
| Tennessee Titans | 3-14 | 0-6 | 284 | 478 |
Jacksonville won the division at 13-4 and was the AFC’s third seed. Houston was a game behind at 12-5, and both went 5-1 inside the division. Indianapolis finished 8-9. Tennessee was 3-14 and lost all six of its division games.
More NFL odds pages
Team pages, where each club’s games and our predictions are listed: Jacksonville Jaguars, Indianapolis Colts, Houston Texans, Tennessee Titans.
What the AFC South winner is priced at in the next rounds is on AFC Championship odds and Super Bowl odds. The rest of our coverage starts at the NFL picks and predictions hub. Paid NFL picks are available from the PicksToday handicappers.