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2026 College Football Week 5 Odds and Predictions

Make sure you check ScoresandStats top handicappers each week of the college football season. They can help you understand how to approach some of these big point spreads and game totals.

Our college football predictions for Week 5 of the 2026 season: 54 games, each with its own page, listed 3 October 2026. Each page gives the line, our number and the call, or says plainly that the numbers do not support a bet.

Last week’s games are on the Week 4 page, and the full list of current predictions is on our college football predictions hub.

Saturday 3 October

Prediction
Akron at Central Michigan Best Pick, Prediction and Odds
Alabama at Mississippi State Best Pick, Prediction and Odds
Arkansas at Texas A&M Best Pick, Prediction and Odds
Arkansas State at Louisiana Best Pick, Prediction and Odds
Army at Louisiana Tech Best Pick, Prediction and Odds
Auburn at Tennessee Best Pick, Prediction and Odds
Baylor at Arizona State Best Pick, Prediction and Odds
Boston College at SMU Best Pick, Prediction and Odds
Bowling Green at Miami (OH) Best Pick, Prediction and Odds
BYU at TCU Best Pick, Prediction and Odds
California at UNLV Best Pick, Prediction and Odds
Cincinnati at Arizona Best Pick, Prediction and Odds
Eastern Michigan at Massachusetts Best Pick, Prediction and Odds
Florida at Missouri Best Pick, Prediction and Odds
Fresno State at Washington State Best Pick, Prediction and Odds
Georgia Southern at Coastal Carolina Best Pick, Prediction and Odds
Indiana at Rutgers Best Pick, Prediction and Odds
Kentucky at South Carolina Best Pick, Prediction and Odds
Marshall at James Madison Best Pick, Prediction and Odds
Maryland at Nebraska Best Pick, Prediction and Odds
Memphis at Charlotte Best Pick, Prediction and Odds
Miami at Clemson Best Pick, Prediction and Odds
Michigan at Minnesota Best Pick, Prediction and Odds
Michigan State at Wisconsin Best Pick, Prediction and Odds
Middle Tennessee at Kansas Best Pick, Prediction and Odds
Navy at Air Force Best Pick, Prediction and Odds
Notre Dame at North Carolina Best Pick, Prediction and Odds
Ohio at Kent State Best Pick, Prediction and Odds
Ohio State at Iowa Best Pick, Prediction and Odds
Oregon State at Colorado State Best Pick, Prediction and Odds
Purdue at Illinois Best Pick, Prediction and Odds
Samford at UAB Best Pick, Prediction and Odds
San José State at Hawai’i Best Pick, Prediction and Odds
Stanford at Wake Forest Best Pick, Prediction and Odds
Syracuse at UConn Best Pick, Prediction and Odds
Temple at South Florida Best Pick, Prediction and Odds
Texas Southern at Florida Atlantic Best Pick, Prediction and Odds
Texas State at San Diego State Best Pick, Prediction and Odds
Texas Tech at Colorado Best Pick, Prediction and Odds
Toledo at Ball State Best Pick, Prediction and Odds
UCF at Houston Best Pick, Prediction and Odds
UL Monroe at South Alabama Best Pick, Prediction and Odds
Utah State at Boise State Best Pick, Prediction and Odds
UTEP at New Mexico Best Pick, Prediction and Odds
UTSA at Rice Best Pick, Prediction and Odds
Vanderbilt at Georgia Best Pick, Prediction and Odds
Virginia at Florida State Best Pick, Prediction and Odds
Washington at USC Best Pick, Prediction and Odds
West Virginia at Iowa State Best Pick, Prediction and Odds
Western Michigan at Buffalo Best Pick, Prediction and Odds
Wyoming at North Dakota State Best Pick, Prediction and Odds
Louisville at NC State Best Pick, Prediction and Odds
Old Dominion at Georgia State Best Pick, Prediction and Odds
McNeese at LSU Best Pick, Prediction and Odds

Listed from the live site on 3 October 2026. Lines move through the week; each prediction states when its prices were read.

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