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Game Preview Seattle Seahawks @ Indianapolis Colts
The Seattle Seahawks travel east to face the Indianapolis Colts on December 14, 2025, in a late-season clash with AFC Wild Card implications. Both teams enter the week with .500-level records, making this a must-win scenario as the playoff picture tightens.
Seattle has relied on its veteran core, while Indianapolis continues to build momentum with its young roster and a run-heavy approach. The game presents an intriguing matchup of strength-on-strength: the Colts’ rushing attack versus Seattle’s physical defensive front.
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Odds and Key Information
The opening line had Indianapolis as a 1.5-point home favorite, with the total set at 44.5. As injury reports developed, the spread shifted slightly, reflecting betting confidence in Seattle’s experience. The over/under has stayed stable, indicating balanced market action on the total.
Understanding how line moves matter in matchups like these is essential. Use our complete NFL betting guide to sharpen your line-reading skills and improve closing line value.
Seattle Seahawks Outlook
The Seattle Seahawks are looking to regain momentum after an up-and-down stretch. Geno Smith has had flashes of high efficiency, especially when protected well, but offensive line issues have plagued consistency. Kenneth Walker remains a game-breaking talent in the run game, and the emergence of rookie wideout depth has helped stretch opposing secondaries.
Defensively, the Seahawks have shown improvement in red zone stops and are generating takeaways more consistently than earlier in the season. However, they’ve struggled against mobile quarterbacks and play-action-heavy systems—both of which are central to the Colts’ identity.
For matchup-specific betting trends tied to Seattle’s road performance, review our recent coverage on NFL underdog opportunities in December.
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Indianapolis Colts Outlook
The Indianapolis Colts continue to outperform preseason expectations. Their offensive success is anchored by a powerful run game led by Jonathan Taylor, who has eclipsed 1,000 yards and remains the focal point of their offense. Quarterback play has stabilized, and the Colts are converting over 42% of third downs at home.
Defensively, Indianapolis is average statistically but opportunistic. They’ve forced multiple turnovers in four of their last six games and lead the AFC in fumble recoveries. If they can slow Seattle’s early down production and create third-and-long situations, they’ll be in position to dictate the game tempo.
For deeper projections on Indianapolis’s postseason chances, check our latest breakdown of AFC playoff predictions.
Key Matchup
This game may be decided in the trenches. Seattle’s run defense, ranked top 12 in yards per carry allowed, will face one of the NFL’s most volume-heavy backfields. If the Seahawks can contain Taylor and force Indianapolis to lean on its passing game, they’ll increase their turnover potential.
On the flip side, Seattle must protect Geno Smith against a Colts defensive front that ranks in the top 10 in quarterback hurries. Expect a heavy dose of quick outs and screen plays early from Seattle to neutralize the pass rush.
To explore player-focused matchup betting, dive into the best angles in our NFL prop betting preview.
Betting Trends
Seattle is 4-1 against the spread in its last five games against AFC teams and 3-2 ATS on the road this season. Indianapolis has covered four of its last six games at home and is 5-1 ATS when rushing for over 130 yards. The under has hit in three straight Colts games, largely due to clock control and red zone field goal drives.
For data-driven breakdowns of NFL market performance, explore our weekly NFL betting blog for actionable trend summaries.
Prediction
This game sets up as a close, low-scoring contest decided by turnovers and third-down efficiency. Seattle’s veteran playmakers give them a slight edge, but Indianapolis’ home field and rushing attack will keep it close.
Final prediction: Seahawks 21, Colts 20
Spread Pick: Seahawks +1.5
Total Lean: Under 44.5
For more cold-weather game breakdowns and late-season betting tips, read our analysis on Sunday Night Football odds and primetime trends.
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