Week 13 of the 2025-26 NFL season wraps up with a Monday Night Football battle between two exciting, young quarterbacks as Drake Maye and the New England Patriots host Jaxson Dart and the New York Giants.

The Giants (2-10) have fired their head coach and defensive coordinator over the last month, as they’re mired in a six-game losing streak. Let’s also not forget that this streak began when rookie RB Cam Skattebo went out with a season-ending injury. The Giants had won two of three games before this losing streak due to Dart and Skattebo’s playmaking.

New York was very competitive in Week 12 as they lost in OT at Detroit. In fact, the Giants have lost three games in a row by one score. The return of Dart will make this team more competitive on MNF.

While they have won nine games in a row, the Patriots (10-2) have won three of their last four games via six points or less. They beat the Bengals via six points, but Cincy was driving down to win the game before falling short.

In Week 11, the Pats beat the Jets via 13 points, but squeaked by the Buccaneers in Week 10 via five points. Both of New England’s losses this year have been at home.

New England has Super Bowl aspirations after shocking the league by not only leading the AFC East division heading into December but by also being tied for the best record in the NFL as of this writing.  

Currently, this game is favored towards the Patriots by a touchdown, according to the latest NFL betting lines. With that said, let’s dive deeper into the latest MNF odds, courtesy of the top sports betting sites, and make our Week 13 NFL picks for the New York Giants vs. New England Patriots.

What Channel Is Monday Night Football On?

• Monday Night Football Channel: ESPN
• Monday Night Football Time: 8:15pm ET
• Monday Night Football Announcers: Joe Buck and Troy Aikman

The New York Giants vs. New England Patriots will kick off at 8:15pm ET live from Gillette Stadium in Foxborough, MA.

Monday Night Football Odds

The following Monday Night Football odds are courtesy of ScoresandStats:

Keep an eye on the latest NFL odds for MNF and monitor how the lines change up until kickoff.

The line first opened with the New England Patriots favored by 3 points and sporting a -155 moneyline. The spread went as high as 7.5 points over the week before settling at seven points. The Patriots’ moneyline went all the way up to -440 before settling at a range of -350 to -390 odds.

The New York Giants opened as a +130 Underdog before seeing their line go as high as +325 odds. Currently, New York’s moneyline sits between +275 and +305. The Total opened at 42.5 points and has slowly climbed up to the current Over/Under of 46.5 points.  

The 49ers steamrolled Carolina last week and boosted our MNF record to 9-7 SU on the season. We’re on a heater with six wins in the last seven MNF games.  

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Monday Night Football Betting Trends

The following Monday Night Football betting trends include data from last season:

New York Giants Betting Trends

• 0-6 SU in last six games
• 0-12 SU in last 12 road games
• 1-4 SU in last five AFC East games
• 5-2 ATS in last seven games
• Under is 13-5 in last 18 AFC games

New England Patriots Betting Trends

• 9-0 SU in last nine games
• 4-1 SU in last five home games
• 0-5 SU in last five December games
• 7-2 ATS in last nine games
• 0-6 ATS in last six NFC East games
• Over is 5-1 in last six NFC games

Monday Night Football Matchup

These two NFL Teams have played against each other 14 times, and the series is tied with seven wins apiece. However, it’s the New York Giants that have won four of the last six head-to-head meetings including Super Bowl 32 and 36.

These teams last played against each other in November 2023, and the Giants won 10 to 7. New York is 6-1 ATS in their last seven games versus the Patriots. The Under is 8-4 in the last 12 meetings, along with going 4-1 in the last five games at Foxboro.

Monday Night Football Predictions

Let’s take a look at the participants in this week’s Monday Night Football game, and make our winning NFL picks: 

New York Giants Monday Night Football

As mentioned, the Giants have lost six games in a row. However, they have been mostly competitive over that stretch. Nevertheless, this team has fired more people than any other franchise in the NFL so far. Furthermore, they’ve also suffered key injuries that derailed their full potential like the losses of Nabers and Skattebo.

With that said, the Giants get Dart back after he missed playing time due to a concussion. The rookie brings swagger to this offense and a hustle that New York (New Jersey) has fully embraced.

The Giants have a decent offense that’s in the top half of the league for many key categories. They average 348.5 total yards per game (11^th), 124.5 rushing ypg (9^th), and 224 passing ypg (13^th). And they do all of this without the key players above.

To have a real shot at winning, the Giants will need to protect Dart and use the short passing game to resemble a rushing attack since New England is the second-best run stopping team in the NFL as they allow only 87.7 ypg.

Another area where New York needs to improve on MNF is in the red zone. They sport the third lowest red zone TD rate (47.62%). But the Patriots allow the highest red zone TD percentage (73.08%). So, if they Giants can get into the red zone, then they have a real shot at scoring TDs and must do so if they want to win outright.

New England Patriots Monday Night Football

New England’s key to success is running the ball. The Giants allow the most rushing yards in the NFL at 157.2 ypg. Yet, the Patriots are 19^th in the league at 112.4 ypg. Plus, they only run 46.83% of the time. I can see New England flipping that script on Monday as they lean on the run due to New York’s ineptness to stop it.

One area of concern for this Patriots offense is that they give up the 6^th highest sack rate which is bad news when facing an aggressive New York front four. I expect short, quick passes for Maye in this matchup especially if the Giants are getting after him right out of the gate.

Defensively, look for the Patriots to come after Dart and not allow him time to throw the ball. I also expect the Pats to have a spy as the rookie QB has shown a knack for extending plays and picking up first downs with his legs. He’s also a red zone threat with his legs, which New England will definitely be mindful of.

Who Is Winning Monday Night Football?

It’s hard to see New England losing this game outright. The Giants have lost 12 straight road games including all seven Away games this season to date. The Patriots are 4-1 SU in their last five home contests. I expect New England to improve that mark to 5-1 SU in their last six.

However, I do like the Giants to cover the seven points. New England is 0-6 ATS in their last six NFC East games. New York has gone 6-1 ATS in their last seven matchups versus the Patriots and 5-2 ATS in their last seven overall games despite losing six of them. I see a backdoor cover in this matchup or a Patriots victory via game-winning score.

I also like the Under in this matchup. The Under is 4-1 in the last five games between these two teams at Foxboro and 8-4 in their last 12 overall matchups. For the Giants, the Under is 13-5 in their last 18 games against the AFC.

Bet: New England Patriots (-350), Giants +7 (-110), Under 46.5 (-110)

Monday Night Football Prop Bets

Let’s take a look at some of the best Player props and Game prop bets for this Monday Night Football matchup:

TreVeyon Henderson Rushing Yards

• Over 60.5 yards (-110)
• Under 60.5 yards (-110)

What do you get when you put an explosive running back against the league’s worst rush defense? In short, you get over 60.5 rushing yards for Henderson.

The rookie running back has gone over that mark in three straight games, and four of his last five. He’s been a dynamic weapon in New England’s backfield and is a dual threat for this Patriot’s offense. I see at least 61 rushing yards on Monday night.

Bet: Over 60.5 yards (-110)

Drake Maye Passing Yards

• Over 240.5 yards (-110)
• Under 240.5 yards (-110)

For the season, Drake Maye is averaging 260.8 passing yards per game. He’s gone over 241 passing in nine of his 12 starts so far, which includes five games in a row. I expect the talented second-year QB to eclipse that mark for a sixth straight time as he lights up this New York secondary.

Bet: Over 240.5 yards (-110)

Jaxson Dart Rushing Yards

• Over 28.5 yards (-110)
• Under 28.5 yards (-110)

Despite his reckless running style, I see Dart surpassing 29 rushing yards this Monday. In his seven starts, Dart has gone over that mark in five of them. In fact, he’s averaging over 45 rushing yards per game over that span including eclipsing 50 rushing yards in five games so far.

I see Dart being aggressive and running the ball to pick up first downs on busted plays and also trying to rush for a touchdown when New York is in the red zone against the NFL’s worst red zone defense.

Bet: Over 28.5 yards (-110)

Best Bets For Monday Night Football

Check out our best bets for Monday Night Football:

• New England Patriots -350
• Jaxon Dart over 28.5 rushing yards (-110)
• Drake Maye over 240.5 passing yards (-110)

The Patriots are the better team in this matchup no matter which side of the ball that you look at. While having Dart will make the Giants more competitive and possibly even cover the seven-point spread, New England is just too good from the coaching staff down to the players. They will win this game outright.

Dart is averaging over 45 rushing yards in his seven starts and has eclipsed 50 rushing yards in five of those seven games. I see the talented rookie QB getting at least 30 rushing yards this week.

Last, but not least, Drake Maye has gone over 241 passing yards in nine of his 12 starts which includes five straight games.

If you put these best Week 13 MNF bets into a parlay, then you will win $369 for every $100 wagered. That’s over a 3x on your parlay card.

If this interests you, then check out our best NFL parlays of the week. We also have weekly College Football parlays, as well.

Monday Night Football Song

Monday Night Football’s theme “Heavy Action” has become a pop-culture staple as generations of fans will instantly recognize the theme song within the first few notes.

Yet, over time, broadcast networks have tried to retool the MNF song to add an extra layer of entertainment, importance, and relevance. For over two-decades, Monday Night Football belonged to Hank Williams Jr. and his hit “All My Rowdy Fans Are Coming Over Tonight.”

In 2023, ESPN debuted a new opening song. They took one of the 80’s biggest hits “In The Air Tonight” by Phil Collins and modernized it with an all-star collaboration from Christ Stapleton, Snoop Dogg and Cindy Blackman Santana. As of now, this rendition is expected to remain the Monday Night Football song for the 2025-26 season.

Monday Night Football Schedule