Week 11 of the 2025-26 NFL season opens with and AFC East clash as the New England Patriots host the New York Jets on  Thursday Night Football.

Sunday’s slate of action features an International Game as the Miami Dolphins and Washington Commanders battle in Madrid, Spain. This means that NFL bettors will have to get up early for this matchup.

Later in the day, there are a handful of games that have us excited for Week 11 including: the Buccaneers vs. Bills, Bengals vs. Steelers, Bears vs. Vikings, and Chiefs vs. Broncos.

However, the main event for Week 11 is the Sunday Night Football game where the Philadelphia Eagles host the Detroit Lions. Could this be an early NFC Championship preview where the winner becomes the Super Bowl favorite?

Unlike in Week 8, where there were six teams on bye, Week 11 will only feature two NFL teams on a bye this week: Colts and Saints.

Without any further delay, let’s take a look at the NFL Week 11 odds and make our early Week 11 picks. There’s no shame in getting your Week 11 NFL bets in early as there is some value on the boards.

NFL Week 11 Schedule

NFL Week 11 Odds

As we dive into the early Week 11 NFL odds, there are some notable betting lines that jump off the page at the best sports betting sites.

The Buccaneers vs. Bills have the highest Total for the Week at 49.5 points. These are two explosive offenses doing battle in Buffalo, where the mid-November weather could play a role. You definitely want to pay attention to the weather for this weekend and the available player prop bets as well.

The Ravens are the biggest favorite of the week as they check in at -380 odds and favored by 8.5 points over the Browns. These numbers can easily balloon by time we get to November especially if Cleveland is in the running for the #1 pick in the 2026 NFL Draft.

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NFL Week 11 Predictions

Let’s take a look at the full slate of NFL Week 11 matchups and make our NFL picks for each game.

New York Jets vs. New England Patriots Odds

Last year, the New York Jets and New England Patriots split their games. In fact, the Jets won two in a row before New England took their 2024 home matchup. With that said, the Patriots own this rivalry.

In 132 meetings coming into this season, the Patriots have a 75-56-1 record. Furthermore, they’ve won 16 of the last 18 meetings. The Patriots have also won 13 of their last 14 home games against the Jets.

New York Jets vs. New England Patriots Predictions

This AFC East divisional matchup will most likely decide which team lives in the basement for this season. More than likely, that team will be the New York Jets.

This franchise is in a rebuild mode and under a new coaching staff, along with a new QB. Sportsbooks don’t believe much in the Jets this season and neither do I.

On the other side of the field, I’m a believer in Drake Maye and think he has the potential to be a solid QB in the league. I’m not ready to deem him a Top 10 QB, but a Top 15-20 is definitely possible this season.

The Patriots should be the better team in this matchup and win at home over their divisional rival. Keep an eye on how good or bad the Jets are in the prior months because this spread could provide value one way or another.

Bet: New England Patriots (-205), Patriots -5.5 (-110)

Washington Commanders vs. Miami Dolphins Odds

After 16 head-to-head meetings, the Miami Dolphins hold the advantage with a 10-6 record. They’ve also won three of the last four meetings against the Washington Commanders.

These two teams last met in 2023, and the Dolphins crushed the Commanders by the score of 45-15. This game will be played in Spain, so neither will have the home-field advantage.

Washington Commanders vs. Miami Dolphins Predictions

Like the Jets, I’m not a believer in the Miami Dolphins. This team has failed to live up to its potential over the last few years and I think this season’s failures could result in an overhaul.

The Dolphins better soak up the Spanish scenery because this is the closest thing they will get to celebrating a Super Bowl.

Unlike Miami, Washington has a bright future as they’re led by second-year QB sensation Jayden Daniels. The addition of wide receiver Deebo Samuel should be a key piece to this offense improving on its success from last year.

Whether it’s behind a strong defensive performance or a high-scoring showdown, the Commanders will win this game by a touchdown.

Bet: Washington Commanders (-205), Commanders -4.5 (-110)

Los Angeles Chargers vs. Jacksonville Jaguars Odds

This Week 11 matchup marks the 15^th that these two teams have played against each other. Currently, the Los Angeles Chargers hold advantage with a 9-5 series record. Yet, the Jacksonville Jaguars have won two in a row, including the remarkable comeback in the January 2023 AFC Wild Card matchup.

The Chargers last beat the Jaguars in 2020, but are just 2-3 since 2017. Yet, the series is tied 4-4 when these two teams play at Jacksonville.

Los Angeles Chargers vs. Jacksonville Jaguars Predictions

For the life of me, I can’t understand how the Jaguars are this close in odds to the Chargers. These two teams have a chasm of disparity in overall talent and coaching.

The Jaguars have dropped the ball figuratively and literally over the last few seasons, which has resulted in another franchise reset.

The Chargers continue on their Playoff trajectory and should be in the hunt for another Wild Card spot this season, just like last year.

I love the value we’re getting with the Chargers as they should win this game by at least a field goal behind their strong rushing attack and an opportunistic defense. Additionally, Justin Herbert is the best QB in this came and he will make enough winning plays for LA compared to Trevor Lawrence with the Jags.

Bet: Los Angeles Chargers (-122), Chargers -1.5 (-110)

Carolina Panthers vs. Atlanta Falcons Odds

After 60 meetings heading into this season, the Atlanta Falcons have a sizable lead with a 37-23 record over the Carolina Panthers. However, the Panthers have won three of the last five games.

In fact, Carolina’s win in January, pretty much eliminated the Falcons from the Playoffs as they needed to win and for the Bucs to lose.

Atlanta has a 21-9 record at home against Carolina. But the Panthers have taken three of the last five on the road in this series.

Carolina Panthers vs. Atlanta Falcons Predictions

This NFC South battle could tell us which team is really in the hunt to win the division or a Wild Card spot, and which team was just smoke and mirrors for the first half of the season.

There’s plenty of pre-season optimism in Carolina that this team could end up surprising the league. While, I believe they will be much better than last year’s team, I have a hard time thinking that they will challenge for a Playoff spot.

Yet, that’s what I believe about the Falcons. I see this team being a Playoff contender whether it’s by winning the division or fighting for one of the final Wild Card spots.

With that said, Carolina beat the Falcons last year and I think they can cover the spread this week. However, I’m taking Atlanta to snatch the victory on a game-winning field goal.

Bet: Atlanta Falcons (-165), Panthers +3 (-110)

Tampa Bay Buccaneers vs. Buffalo Bills Odds

The buffalo Bills and Tampa Bay Buccaneers have played against each other 13 times and it’s the Bills that hold an 8-5 series lead. Buffalo has won three of the last five meetings including in 2023, when they last played.

At home, Buffalo is 3-0 against the Buccaneers. Their last home game vs. the Bucs came in that 2023 matchup, which the Bills won 24-18. It’s rather surprising that out of the 13 all-time meetings, only three have been in Buffalo.

Tampa Bay Buccaneers vs. Buffalo Bills Predictions

This is going to be one of the more exciting matchups in Week 11. Baker Mayfield vs. Josh Allen was supposed to be one of the top QB battles in the league after they were drafted a handful of years ago.

Well, it didn’t pan out for Mayfield until the last few seasons since joining the Bucs. And, while he has a talented offense built around him, Buffalo is nearly unbeatable at home in the regular season under Sean McDermott.

Allen will outduel Mayfield through the air and on the ground. The latter is the more significant aspect since Tampa Bay is generally a very stingy run defense. So, Allen will have to extend drives with his legs, which he is more than capable of doing.

Eventually, this Bills offense will pull away in the 4^th quarter to win by a comfortable margin of seven or more points.

Bet: Buffalo Bills (-225), Bills -5.5 (-110)

Cincinnati Bengals vs. Pittsburgh Steelers Odds

Coming into this season, the Cincinnati Bengals and Pittsburgh Steelers have played against each other 111 times. The Steelers hold a massive lead in this rivalry with a 71-40 record.

Pittsburgh has also taken three of the last four meetings. However, Cincy won the last time these two teams played in January. In fact, the Bengals are 3-1 in their last four trips to Pittsburgh.

Cincinnati Bengals vs. Pittsburgh Steelers Predictions

By this point of the season, we should have a good idea as to which team will really challenge the Ravens for the AFC North title.

The Steelers have an elite defense, which will keep them in games even when their offense sputters. And, I expect them to sputter at a high clip.

The Bengals have an atrocious defense, which should allow the Steelers to score points. However, I think Cincy’s offense will be too much for Pitt to handle in Week 11.

As we see the Bengals rise up the AFC rankings, I think this is the week that pretty much seals Pittsburgh’s fate on the season; and that is missing the Playoffs.

Bet: Cincinnati Bengals (-120), Bengals -1.5 (-110)

Green Bay Packers vs. New York Giants Odds

After 64 head-to-head meetings, the Green Bay Packers lead this series with a 34-28-2 record. They last faced each other in 2023, and it was the New York Giants that won the game. In fact, the Giants have won two in a row and five of the last eight meetings between these two long-time NFC teams.

Furthermore, the Giants have won three of their last four home games over the Packers. Yet, the series is tied at 18-18-2 all-time at New York.

Green Bay Packers vs. New York Giants Predictions

The Giants are certainly putting together the pieces to become a more competitive team. Unfortunately, they play in a tough NFC East division, and I don’t see them going better than 1-5 or 2-4 at best.

A losing record in their division makes this team even more desperate as they try to beat Playoff-caliber opponents like the Packers. And, I don’t that happening even if it’s a home game.

Green Bay is a better team on both sides of the ball. Their defense will get after NY’s Russell Wilson and force mistakes. Their offense will eventually plow through a feisty Giants defense and break open the game in the second half.

Look for Green Bay to pull away in the fourth quarter as they win by at least a touchdown on the legs of Josh Jacobs and Jordan Love.

Bet: Green Bay Packers (-195), Packers -4.5 (-110)

Houston Texans vs. Tennessee Titans Odds

Coming into this season, the Tennessee Titans hold the advantage with a 24-22 record over the Houston Texans. However, the Texans have won four of the last five meetings including four in a row at Tennessee.

Although the Titans have a 12-11 record at home against the Texans, Houston won there four years in a row and five of their last six trips to Tennessee.

Houston Texans vs. Tennessee Titans Predictions

If there’s any team with the best chance at sweeping through their division, it’s the Houston Texans in the AFC South.

In the AFC East, Buffalo has just as good of a chance, but I do expect the Patriots and Dolphins to finish with above .500 records. In the AFC South, only the Texans will have a winning record.

Now, the Colts could be a surprise team if Anthony Richards lives up to his raw potential. But that is a big “if” as the young QB can’t stay healthy.

Speaking of young QBs, the Titans have a rookie in Cam Ward that will be starting this game. And, he’s going up against an elite defense that will wreak havoc all game long.

Houston’s defense will set the tone for this game, provide the offense with extra possessions and might even score points themselves. This game should be a blowout win for the Texans.

Bet: Houston Texans (-155), Texans -3 (-110)

Chicago Bears vs. Minnesota Vikings Odds

These two divisional rivals have played against each other 128 times prior to this season. The Minnesota Vikings hold the advantage with a 68-58-2 record.

Minnesota has also dominated the Chicago Bears in recent years as well. The Vikings have won eight of the last 10 meetings including sweeping the Bears last year.

The Vikings have won three of their last four games at home over Chicago and hold an all-time record of 40-25 in home contests versus the Bears.

Chicago Bears vs. Minnesota Vikings Predictions

Now that we’re in the second half of the season, it’s important to see which teams are contenders and which are pretenders.

Last year at this point, we though the Bears could be contenders for an NFC Wil Card. Unfortunately, they began a long losing streak that led to the team firing their head coach and other members of the staff.

This year, I think we see a marked improvement that leads to a big NFC North win for the Bears over the Vikings. I am not a big fan of Caleb Williams, but I do expect the second-year QB to flourish under the new offensive system, offensive line, and head coach.

I think Williams will outplay Minnesota’s JJ McCarthy. And, where the Vikings snagged a Wild Card last year, I see the Bears having a better shot at that accomplishment than Minnesota this season.

I’m taking the upset in this matchup as Chicago shows that they’re for real this season.

Bet: Chicago Bears (+110), Bears +2.5 (-110)

San Francisco 49ers vs. Arizona Cardinals Odds

Although the San Francisco 49ers hold the lead in this divisional rivalry with a 36-31 record coming into this season, it’s the Arizona Cardinals that have won two in a row. In fact, the Cardinals swept the 49ers last year, which might shock some of you.

The series is tied 16-16 in games at Arizona, but the Cardinals have won seven of their last 10 games versus the 49ers.

San Francisco 49ers vs. Arizona Cardinals Predictions

This is going to be an exciting game within the NFC West division. We have two teams that are chasing after the Rams to win the division and hoping that they have enough talent on their roster to earn at least a Wild Card spot.

In the case of the 49ers, I don’t think it will happen. Too many departures this offseason will leave the team thin at spots and injuries will catch up once again. Sure, Brock Purdy and George Kittle will do their part to keep this team in the hunt, but games like this one will prove to be their downfall.

I like the Cardinals at home over the 49ers. I think Kyler Murray will create problems for the defense and that this Arizona offense will outscore San Francisco to win by at least a field goal.

Bet: Arizona Cardinals (+100), Cardinals +1.5 (-110)

Seattle Seahawks vs. Los Angeles Rams Odds

This NFC West rivalry is a close one as the Seattle Seahawks hold a slight edge over the Los Angeles Rams with a 28-27 record coming into the season.

The Rams have taken three of the last four and six of the last nine meetings. LA is 15-11 all-time in home games against the Seahawks. Yet, the Rams have won eight of their last 11 home contests in this rivalry. However, Seattle won last year in Los Angeles and have taken two of the last three in LA.

Seattle Seahawks vs. Los Angeles Rams Predictions

The entire NFC West is playing against each other in Week 11, and this is where we will see teams separate themselves from the pack.

I think that the Rams are the team to beat in the NFC West and they will prove that once again, by dispatching the Seahawks in Week 11.

Seattle doesn’t have the offensive firepower to hang with the Rams, and their defense is not at an elite level to where they can slow down LA’s offense.

Eventually, LA’s Matthew Stafford will outduel Seattle’s Sam Darnold and the Rams will pull away in the fourth quarter to win by at least a touchdown. LA’s offense is going to be fun to watch this season and performances like the one in Week 11 will show us why they’re a legit threat in the conference.

Bet: Los Angeles Rams (-195), Rams -4.5 (-110)

Kansas City Chiefs vs. Denver Broncos Odds

With 130 all-time meetings between these two rivals, coming into this season, the Kansas City Chiefs hold the advantage with a 73-57 record. However, the Denver Broncos has taken two of the last three meetings between these rivals.

Both of those wins came in Denver over the last two seasons. Yet, the Chiefs have gone 17-2 over the last 19 meetings between these two foes. In fact, they had won 16 in a row over Denver before the Broncos snapped that streak in October 2023.

Kansas City Chiefs vs. Denver Broncos Predictions

From the NFC West to the AFC West, we have a thrilling matchup as the Chiefs head to Denver to face the confident Broncos team.

Last year, Denver beat up on the Chiefs backups, which pretty much helped them get into the Playoffs. This year, if Denver wants to make the Playoffs, they will have to beat the Chiefs starters.

If there’s one team in the division that can hang with KC, it’s the Broncos.  Defensively, the Orange Crush is back with arguable the top defense in the league. At the very least, it has the best secondary. And, that will be key against a potent KC offense.

Patrick Mahomes is the king of the AFC Conference, and there’s definitely a scenario where this team wins another trip to the Super Bowl this year. However, I think we see Denver announce to the league that they are for real. Meaning, that last year wasn’t a fluke.

And, the Broncos do this by defeating the Chiefs in an epic divisional battle.  

Bet: Denver Broncos (+100), Broncos +1.5 (-110)

Baltimore Ravens vs. Cleveland Browns Odds

With 52 teams played between the old Browns and the new Browns, the series is heavily slanted towards the Baltimore Ravens who hold a 37-15 record.

The Ravens have gone 13-6 over the last 19 meetings between the two teams. Yet, the Cleveland Browns have won two of the last three meetings. Additionally, Cleveland has gone 3-1 in their last four home games versus Baltimore.

Baltimore Ravens vs. Cleveland Browns Predictions

For as thrilling as the Chiefs vs. Broncos is, this game will be the exact opposite. In reality, the only question I have is whether or not the Ravens can win by 10 or more points.

And, I see that happening. Cleveland has played Baltimore tough over the last few years, but the disparity in roster talent and coaching will shine in Week 11.

Baltimore’s defense will suffocate the Browns’ offense. Conversely, look for this Ravens rushing attack to steamroll Cleveland into submission.

I expect this game to be over with by the fourth quarter and for Lamar Jackson to be sitting on the sidelines laughing about the futility of this Cleveland franchise.

Bet: Baltimore Ravens (-380), Ravens -8.5 (-110)

Detroit Lions vs. Philadelphia Eagles Odds

The Philadelphia Eagles hold the slight advantage in this series with an 18-16-2 record. Philly has also won two games in a row over the Detroit Lions with their last meeting coming in 2022, at Detroit.

Prior to that, the Lions had won three in a row over the Eagles. Additionally, Detroit is 9-10 in games at Philly and have gone 2-1 in their last three trips to the home of the Eagles.

Detroit Lions vs. Philadelphia Eagles Predictions

There are some fun games to watch this week like Bucs vs. Bills and Chiefs vs. Broncos, but this Sunday Night Football game is the main event of Week 11. In fact, it should be a foreshadowing of what we will see in the NFC Championship game.

If there’s any NFC team that can go toe-to-toe with the Eagles, it’s the Lions. Detroit has just as much talent on the offensive side of the ball as Philly does. In fact, I would lean towards the Lions in that matchup.

The question, and difference maker, is the Eagles’ defense. They were one of the best last year and should be a Top 10 unit once again this year. The Lions need to remain healthy and play an A-game defensively to have a shot at winning.

I think Detroit plays a great game, but Philly wins on the final drive of this contest. However, take the Lions to cover the spread.

Bet: Philadelphia Eagles (-175), Lions +3.5 (-110)

Dallas Cowboys vs. Las Vegas Raiders Odds

These two proud franchises, and crazy fan bases, have seen 13 contests take place between them. The Las Vegas Raiders hold the advantage with a 7-6 record. Their last meeting came in 2021, where the Raiders won in OT at Dallas.

The Dallas Cowboys do hold a 4-3 advantage in games played at the Raiders. Their last road trip in this series came in 2017, when the beat the Raiders in Oakland. They’ve also beat the Raiders in the only game that took place in Los Angeles (1992).

Dallas Cowboys vs. Las Vegas Raiders Predictions

This Monday Night Football features two of the most die-hard fanbases in the league. It also features two teams that have been huge disappointments over the last decade.

Yet, between the two, the Cowboys have a far better shot at making the Playoffs than the Raiders do. In fact, Las Vegas has no business of even being this close in the odds.

The Silver and Black are rebuilding this year, under new coach Pete Carroll. They will need another offseason to get more of their players into this system.

Dallas should rebound nicely from last year’s massive failure. A healthy Dak Prescott will enjoy a rebound year as well, especially with Lamb and Pickens as his top receivers along with what should be a dependable running game.

I think Dallas wins this matchup easily, and that this spread is easy money!

Bet: Dallas Cowboys (-120), Cowboys -1.5 (-110)

NFL Week 11 Best Bets

Check out our best NFL bets for Week 11:

• Los Angeles Chargers  (-122)
• Houston Texans (-155)
• Dallas Cowboys -1.5 (-110)

I must admit, these best bets are solid. In fact, I love these Week 11 best bets as a three-leg parlay.

All three of these teams are much better than their counterparts. Even though they’re all road teams in Week 11, the Chargers are better than the Jags, the Texans are superior to the Titans, and the Cowboys have too much talent to lose to the Raiders.

I expect all three of these teams to win comfortably in their respective matchups. In fact, we could see victories of six or more points for each of them.

Furthermore, each one of these teams (Chargers, Texans, Cowboys) have the better QB in their respective games along with the better head coaches. If you want to throw another team into this week’s best bets, and bump up your parlay winnings even more, then take the Bills at home.

If you want to combine all three of these picks into an NFL parlay, then you would win $472 on a $100 wager.