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Big East action hits Hinkle Fieldhouse on Tuesday night as Butler hosts DePaul in a matchup tipping at 7:30 PM ET. The Bulldogs are 7.5-point favorites at home and listed at -379 on the moneyline. DePaul enters as a +282 underdog, with the total set at 150.5. Both teams are searching for consistency in conference play, but Butler has been significantly stronger at home. DePaul has struggled to keep games close on the road, especially against disciplined defensive teams like Butler. The Blue Demons are giving up too many clean looks, and their inability to control tempo has led to extended runs by opponents. Butler isn’t perfect, but they defend well at home and tend to win the shot quality

Tuesday night brings a fast-paced A-10 matchup as Saint Louis visits Duquesne at UPMC Cooper Fieldhouse in Pittsburgh. Tipoff is set for 7:00 PM ET, with the Billikens installed as 9.5-point road favorites and priced at -454 on the moneyline. Duquesne comes in at +333, while the total is sitting at a lofty 164.5. Saint Louis has the edge in just about every category — but covering this number away from home might be trickier than it looks. Both teams like to play fast, which pushes the total high. But Saint Louis brings better efficiency and guard depth, while Duquesne has struggled to keep pace with higher-end offenses. This game could get wild, but there’s a clear edge if you

Big Ten play rolls on Tuesday night with a one-sided matchup on paper, as Michigan hosts Indiana at the Crisler Center. Tipoff is set for 7:00 PM ET. The Wolverines are laying a massive 15.5 points at home and are -1933 on the moneyline. Indiana enters as a +833 underdog, while the total is posted at 162.5. This is one of the largest spreads of the night — and possibly still not large enough given recent form. Michigan is surging offensively, especially at home, and Indiana just hasn’t had answers on the road against top-tier teams. While the total is elevated, it reflects Michigan’s pace and scoring efficiency — and the Hoosiers’ ongoing struggles defending perimeter-heavy teams. These are the

Oklahoma hits the road Tuesday, January 20, 2026, for an SEC matchup with South Carolina at Colonial Life Arena in Columbia, with tip set for 7 p.m. ET on SECN. Both teams are sitting at 1-4 in league play, so this is one of those early-January swing games that can keep a season from drifting. The market is basically calling this a pick’em. South Carolina has been solid at home (9-4 overall, 9-3 in true home games), while Oklahoma has been shaky in true road spots (1-6 away, 1-3 in true road games). That clash is the entire handicap: Oklahoma’s offense travels, but South Carolina’s building has been a problem for visitors. These are the current betting lines, and bettors