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Duke Blue Devils vs Michigan Wolverines Picks and Predictions February 21st 2026
Duke and Michigan meet Saturday night at Capital One Arena in Washington, DC, and it’s a true neutral-site game with top-end stakes. Michigan enters ranked No. 1 at 25-1 and has not lost away from home, while Duke is ranked No. 3 at 24-2 and has been crushing opponents during a recent run. The market is still giving Michigan the edge at -3.5, which tells you oddsmakers trust the Wolverines’ baseline offense and their ability to win a possession game when the talent level is even. For bettors, this handicap comes down to shot quality and which team controls the “easy points” layer. Both offenses have the ability to score without relying on late-clock hero ball, and both can rebound
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Southern Illinois Salukis vs Northern Iowa Panthers Picks and Predictions February 21st 2026
Southern Illinois heads to Cedar Falls on Saturday night for a Missouri Valley matchup with Northern Iowa at the McLeod Center, and the market is pricing in a meaningful home-court edge. Northern Iowa is laying -6.5 with a strong 13-3 home record, while Southern Illinois has been far less reliable away from home at 5-9. That split matters in the MVC, where pace is slower, possessions are more valuable, and a small efficiency edge can create separation over 40 minutes. This total also tells you exactly what kind of game the books expect. At 132.5, the market is anticipating a controlled, halfcourt-heavy matchup with long possessions and fewer “easy points.” In that type of environment, an underdog is often live
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Loyola Marymount Lions vs San Diego Toreros Picks and Predictions February 21st 2026
Loyola Marymount heads to San Diego on Saturday night for a West Coast Conference matchup at Jenny Craig Pavilion, and the market is giving the Lions a small road-favorite role at -3.0. That number is more about matchup and recent head-to-head than season résumé. Loyola Marymount is 13-15 and has struggled away from home at 3-7, while San Diego is 11-17 but has been more competitive at home with a 9-7 record. In other words, this line is asking you to decide whether Loyola Marymount’s offensive profile and prior success against the Toreros outweigh the home-floor edge. The total is set at 150.5, which fits a game where both teams can score, but also one where one cold stretch can
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St. Bonaventure Bonnies vs Richmond Spiders Picks and Predictions February 21st 2026
St. Bonaventure heads to the Robins Center on Saturday night for an Atlantic 10 matchup with Richmond, and the market is calling this a tight game with a modest home edge. Richmond is laying -2.5 with a -150 moneyline, which lines up with its 10-6 home record and the idea that the Spiders are more likely to execute cleanly late in a close finish. St. Bonaventure is sitting at 14-12 overall and has been competitive away from home, so the Bonnies are not being priced like a team that is outclassed, they’re being priced like a team that has to prove it can close on the road against a solid A-10 home group. The other key factor is the total.
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North Florida Ospreys vs Stetson Hatters Odds and Predictions February 21th, 2026
North Florida travels to the Edmunds Center in DeLand, Florida on Saturday, February 21, 2026 at 3:30 PM ET for a key ASUN conference showdown against Stetson. With both teams battling for late-season positioning, this matchup carries weight in the standings and presents one of the highest totals on the board. Stetson enters as a 3.5-point home favorite, priced at -150 on the moneyline. North Florida sits at +3.5 with +125 value to win outright. The total is set at 161.5, one of the more aggressive numbers on the slate, signaling expectations of pace, perimeter shooting, and transition opportunities. With a spread under two possessions and a total north of 160, this game profiles as a high-variance contest where tempo,

Jacksonville State Gamecocks vs Sam Houston Bearkats Picks and Predictions February 21st,2026

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The Jacksonville State Gamecocks travel to Bernard G. Johnson Coliseum in Huntsville TX on Saturday, February 21st at 3:30 PM ET for … more

Valparaiso Beacons vs UIC Flames Odds and Predictions February 21th, 2026

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Valparaiso heads to Credit Union 1 Arena in Chicago, Illinois on Saturday, February 21, 2026 for a late-season Missouri Valley Conference matchup … more

Arizona Wildcats vs Houston Cougars Picks and Predictions February 21st, 2026

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The Arizona Wildcats travel to the Fertitta Center in Houston TX on Saturday, February 21st for a high-level conference clash against the … more

Washington Huskies vs Maryland Terrapins Odds and Predictions February 21th, 2026

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Washington travels to the XFINITY Center in College Park, Maryland on Saturday, February 21, 2026 for a high-profile late-season conference matchup against … more

UNLV Runnin’ Rebels vs Air Force Falcons Picks and Predictions February 21st, 2026

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The UNLV Runnin’ Rebels travel to Clune Arena in Colorado Springs CO on Saturday, February 21st for a Mountain West matchup against … more