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College Football Week 10 Odds and Schedule

2025 NCAAF Week 10 Odds

College football Week 10 of the 2026 season runs from Tuesday 3 to Saturday 7 November: 63 games on the FBS schedule, 18 of them with a team from the AP Top 25. Six of those match two ranked teams: No. 11 Texas at No. 23 Missouri, No. 8 BYU at No. 6 Utah, No. 10 Alabama at No. 15 LSU, No. 9 Kentucky at No. 16 Tennessee, No. 3 Georgia at No. 12 Ole Miss and No. 1 Miami at No. 5 Notre Dame.

DraftKings had a line on 24 of the 63 games at 15:25 UTC on Sunday 1 November 2026. The college football Week 10 odds table below gives both sides of the spread, the total and the moneyline for each.

The games before these are on the Week 9 page, and every current pick is on our college football predictions hub. For paid picks, see the top sports betting handicappers.

Week 10 ranked games

Rankings are the AP Top 25 released on Sunday 25 October, which ESPN lists as the Week 9 poll. Records are as ESPN listed them at 15:22 UTC on Sunday 1 November 2026. A new poll comes out before Week 10 is played, so the numbers beside these teams can change.

DayGameRecordsWhereKickoffLine
Sat 7 NovNo. 1 Miami at No. 5 Notre DameMiami 8-0, Notre Dame 7-1Notre Dame, IN7:30 PM ETNotre Dame -3.5, total 55.5
Sat 7 NovOregon at No. 2 Ohio StateOregon 5-3, Ohio State 6-2Columbus, OH3:30 PM ETOhio State -10.5, total 45.5
Sat 7 NovNo. 3 Georgia at No. 12 Ole MissGeorgia 7-1, Ole Miss 6-2Oxford, MS7:30 PM ETGeorgia -3, total 56.5
Sat 7 NovNo. 8 BYU at No. 6 UtahBYU 7-1, Utah 8-0Salt Lake City, UT12 PM ETUtah -4.5, total 47.5
Sat 7 NovNo. 7 UCLA at MinnesotaUCLA 8-0, Minnesota 5-3Minneapolis, MN12 PM ETUCLA -6, total 42.5
Sat 7 NovNo. 9 Kentucky at No. 16 TennesseeKentucky 7-1, Tennessee 6-2Knoxville, TN6:15 PM ETTennessee -5.5, total 50.5
Sat 7 NovNo. 10 Alabama at No. 15 LSUAlabama 6-2, LSU 6-2Baton Rouge, LA3:30 PM ETLSU -4.5, total 52.5
Sat 7 NovNo. 11 Texas at No. 23 MissouriTexas 6-2, Missouri 6-2Columbia, MO12 PM ETTexas -3.5, total 48.5
Sat 7 NovWest Virginia at No. 13 Texas TechWest Virginia 5-3, Texas Tech 7-1Lubbock, TX9:30 PM ETNo line
Sat 7 NovMerrimack at No. 14 Wake ForestMerrimack 4-5, Wake Forest 7-1Winston-Salem, NC3:30 PM ETNo line
Sat 7 NovOklahoma at No. 17 FloridaOklahoma 4-4, Florida 5-3Gainesville, FL7:45 PM ETFlorida -5.5, total 48.5
Sat 7 NovCincinnati at No. 18 HoustonCincinnati 5-3, Houston 6-2Houston, TXTime not setNo line
Fri 6 NovVirginia Tech at No. 19 SMUVirginia Tech 6-2, SMU 6-2Dallas, TX7 PM ETSMU -6.5, total 56.5
Sat 7 NovNo. 20 Boise State at Colorado StateBoise State 7-1, Colorado State 3-5Fort Collins, CO6 PM ETNo line
Sat 7 NovIowa at No. 20 NorthwesternIowa 6-2, Northwestern 6-2Evanston, IL7:30 PM ETNorthwestern -1.5, total 42.5
Fri 6 NovTCU at No. 22 ArizonaTCU 4-4, Arizona 6-2Tucson, AZ10:15 PM ETArizona -8.5, total 44.5
Sat 7 NovNo. 24 Oklahoma State at Kansas StateOklahoma State 5-3, Kansas State 4-4Manhattan, KS12 PM ETNo line
Sat 7 NovRutgers at No. 25 WisconsinRutgers 2-6, Wisconsin 5-3Madison, WI4:15 PM ETNo line

One Top 25 team has no game in Week 10: No. 4 Indiana.

College football Week 10 odds

Prices are DraftKings, as ESPN lists them, read at 15:25 UTC on Sunday 1 November 2026. Spread and moneyline are given visitor first, then home; the ranked games come first.

GameSpreadTotalMoneyline
No. 1 Miami at No. 5 Notre DameMiami +3.5 (-105), Notre Dame -3.5 (-115)Over 55.5 (-110), Under 55.5 (-110)Miami +142, Notre Dame -170
Oregon at No. 2 Ohio StateOregon +10.5 (-105), Ohio State -10.5 (-115)Over 45.5 (-110), Under 45.5 (-110)Oregon +310, Ohio State -395
No. 3 Georgia at No. 12 Ole MissGeorgia -3 (-105), Ole Miss +3 (-115)Over 56.5 (-110), Under 56.5 (-110)Georgia -135, Ole Miss +114
No. 8 BYU at No. 6 UtahBYU +4.5 (-110), Utah -4.5 (-110)Over 47.5 (-110), Under 47.5 (-110)BYU +142, Utah -170
No. 7 UCLA at MinnesotaUCLA -6 (-110), Minnesota +6 (-110)Over 42.5 (-110), Under 42.5 (-110)UCLA -218, Minnesota +180
No. 9 Kentucky at No. 16 TennesseeKentucky +5.5 (-110), Tennessee -5.5 (-110)Over 50.5 (-110), Under 50.5 (-110)Kentucky +164, Tennessee -198
No. 10 Alabama at No. 15 LSUAlabama +4.5 (-115), LSU -4.5 (-105)Over 52.5 (-110), Under 52.5 (-110)Alabama +145, LSU -175
No. 11 Texas at No. 23 MissouriTexas -3.5 (-110), Missouri +3.5 (-110)Over 48.5 (-110), Under 48.5 (-110)Texas -162, Missouri +136
Oklahoma at No. 17 FloridaOklahoma +5.5 (-105), Florida -5.5 (-115)Over 48.5 (-110), Under 48.5 (-110)Oklahoma +170, Florida -205
Virginia Tech at No. 19 SMUVirginia Tech +6.5 (-115), SMU -6.5 (-105)Over 56.5 (-110), Under 56.5 (-110)Virginia Tech +170, SMU -205
Iowa at No. 20 NorthwesternIowa +1.5 (-105), Northwestern -1.5 (-115)Over 42.5 (-110), Under 42.5 (-110)Iowa +105, Northwestern -125
TCU at No. 22 ArizonaTCU +8.5 (-105), Arizona -8.5 (-115)Over 44.5 (-110), Under 44.5 (-110)TCU +275, Arizona -345
Ohio at AkronOhio -12.5 (-110), Akron +12.5 (-110)Over 49.5 (-110), Under 49.5 (-110)Ohio -470, Akron +360
Buffalo at Miami (OH)Buffalo +6.5 (-110), Miami (OH) -6.5 (-110)Over 45.5 (-110), Under 45.5 (-110)Buffalo +190, Miami (OH) -230
Ball State at MassachusettsBall State +4.5 (-110), Massachusetts -4.5 (-110)Over 48.5 (-110), Under 48.5 (-110)Ball State +150, Massachusetts -180
Toledo at Sacramento StateToledo -27.5 (-110), Sacramento State +27.5 (-110)Over 51.5 (-110), Under 51.5 (-110)Toledo -4500, Sacramento State +1700
Central Michigan at Eastern Michigan (neutral site)Central Michigan +1.5 (-110), Eastern Michigan -1.5 (-110)Over 46.5 (-110), Under 46.5 (-110)Central Michigan -102, Eastern Michigan -118
UTSA at Florida AtlanticUTSA -6.5 (-115), Florida Atlantic +6.5 (-105)Over 71.5 (-110), Under 71.5 (-110)UTSA -245, Florida Atlantic +200
James Madison at Southern MissJames Madison -14 (-110), Southern Miss +14 (-110)Over 55.5 (-110), Under 55.5 (-110)James Madison -520, Southern Miss +390
South Florida at East CarolinaSouth Florida -1.5 (-105), East Carolina +1.5 (-115)Over 45.5 (-110), Under 45.5 (-110)South Florida -112, East Carolina -108
Nebraska at IllinoisNebraska -5.5 (-105), Illinois +5.5 (-115)Over 48.5 (-110), Under 48.5 (-110)Nebraska -198, Illinois +164
New Mexico at NevadaNew Mexico -12.5 (-110), Nevada +12.5 (-110)Over 43.5 (-110), Under 43.5 (-110)New Mexico -455, Nevada +350
UCF at KansasUCF +2.5 (-110), Kansas -2.5 (-110)Over 48.5 (-110), Under 48.5 (-110)UCF +110, Kansas -130
Michigan State at MichiganMichigan State +14 (-110), Michigan -14 (-110)Over 39.5 (-110), Under 39.5 (-110)Michigan State +490, Michigan -675

No line was posted on the other 39 games.

Our college football predictions bet a spread only when our own number for the game is at least 3 points from the posted line, and say no bet when it is closer. No Week 10 game has a prediction yet, so this page makes no pick.

College football Week 10 schedule

Kickoff times are US Eastern.

Tuesday 3 November

KickoffGameTV
7 PM ETOhio at AkronESPN2
8 PM ETBuffalo at Miami (OH)ESPN

Wednesday 4 November

KickoffGameTV
7 PM ETBall State at MassachusettsESPNU
7 PM ETToledo at Sacramento StateCBSSN
7:30 PM ETCentral Michigan at Eastern Michigan (neutral site)ESPN2

Thursday 5 November

KickoffGameTV
7:30 PM ETUTSA at Florida AtlanticESPN
8 PM ETJames Madison at Southern MissESPN2

Friday 6 November

KickoffGameTV
7 PM ETVirginia Tech at No. 19 SMUESPN
7:30 PM ETSouth Florida at East CarolinaESPN2
8 PM ETNebraska at IllinoisFox
9 PM ETNew Mexico at NevadaCBSSN
10:15 PM ETTCU at No. 22 ArizonaESPN

Saturday 7 November

KickoffGameTV
12 PM ETFlorida State at Boston CollegeACC Network
12 PM ETNo. 24 Oklahoma State at Kansas StateTNT, HBO Max
12 PM ETNo. 7 UCLA at MinnesotaFox
12 PM ETNo. 11 Texas at No. 23 MissouriESPN
12 PM ETClemson at SyracuseESPN2
12 PM ETTulsa at TulaneESPNU
12 PM ETNorth Carolina at UConnCBSSN
12 PM ETNo. 8 BYU at No. 6 UtahABC
12:30 PM ETDuke at NC StateCW
12:30 PM ETMaryland at PurdueBTN
12:45 PM ETArkansas at AuburnSEC Network
1 PM ETOld Dominion at Coastal CarolinaESPN+
2:30 PM ETGeorgia State at App StateESPN+
3 PM ETUL Monroe at Arkansas StateESPN+
3 PM ETDelaware at Kennesaw StateESPN+
3 PM ETTexas A&M at South CarolinaESPN
3:30 PM ETMarshall at Georgia SouthernESPN+
3:30 PM ETNo. 10 Alabama at No. 15 LSUABC
3:30 PM ETWestern Kentucky at Middle TennesseeESPN+
3:30 PM ETTemple at NavyCBSSN
3:30 PM ETOregon at No. 2 Ohio StateCBS
3:30 PM ETCharlotte at UABESPN+
3:30 PM ETMerrimack at No. 14 Wake ForestACC Network
3:30 PM ETPenn State at WashingtonFS1
3:45 PM ETUCF at KansasESPN2
4 PM ETMissouri State at Florida InternationalESPN+
4 PM ETRice at North TexasESPNU
4 PM ETNorthern Illinois at San José StateMW+
4 PM ETLouisiana Tech at TroyESPN+
4:15 PM ETVanderbilt at Mississippi StateSEC Network
4:15 PM ETRutgers at No. 25 WisconsinBTN
5 PM ETSouth Alabama at LouisianaESPN+
6 PM ETNo. 20 Boise State at Colorado StateUSA Net
6:15 PM ETNo. 9 Kentucky at No. 16 TennesseeESPN
7 PM ETSam Houston at Jacksonville StateCBSSN
7:30 PM ETColorado at Arizona StateESPN2
7:30 PM ETAir Force at ArmyCBS
7:30 PM ETLouisville at Georgia TechACC Network
7:30 PM ETMichigan State at MichiganPeacock
7:30 PM ETIowa at No. 20 NorthwesternFox
7:30 PM ETNo. 1 Miami at No. 5 Notre DameNBC
7:30 PM ETNo. 3 Georgia at No. 12 Ole MissABC
7:45 PM ETOklahoma at No. 17 FloridaSEC Network
8 PM ETLiberty at New Mexico StateESPNU
9:30 PM ETWest Virginia at No. 13 Texas TechESPN
9:30 PM ETHawai’i at UTEPFS1
9:30 PM ETFresno State at Utah StateUSA Net
10:30 PM ETTexas State at Oregon StateCW
10:30 PM ETWyoming at UNLVCBSSN
Time not setIowa State at Baylor–
Time not setCincinnati at No. 18 Houston–

Schedule, rankings and records: ESPN, read at 15:22 UTC on Sunday 1 November 2026. Odds: DraftKings as ESPN lists them, read at 15:25 UTC on Sunday 1 November 2026.

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