Arizona Cardinals

The Cardinals covered the spread once in eight home games in 2025, tied with one other team for the worst home record against the line in the NFL. On the road they covered five of nine, and our Arizona Cardinals predictions and odds for each game are above.

A home record nobody could back

Three wins, 14 losses and six covers in 17: that was Arizona’s 2025 regular season. That cover rate tied for 30th of 32. Split by venue, the picture changes. At home: 1-7 straight up, one cover in eight. Away: 2-7, five covers in nine, a rate only 11 NFL teams beat.

The one home cover was a loss, 23-27 to Green Bay getting 6.5. The one home win, 27-22 over Carolina, fell short of a 6.5-point spread.

Fourteen times the underdog

Arizona got points in 14 games and won one of them: 27-17 at Dallas, at +155. Getting points, they covered 5 of 14. Laying them, three times, they went 2-1 and covered once, and the shortest-priced loss of the year came there: a 21-22 home loss to Tennessee at -450.

They gave up 28.71 points a game; only three NFL teams allowed more. Their longest winning run all year was two games, the opening pair.

Backing Arizona blind

One unit on the Cardinals in all 16 priced games lost 10.76 units. One NFL team lost more. Of that, 10.45 went on the 13 priced underdog games, and even the three as favorites lost 0.31. The three wins returned 0.69 units in the first two weeks and 1.55 at Dallas; every other priced game was a loss. December was 0-4 with no cover, and the season ended on nine straight losses.

The NFC West

The division went 0-6: two losses apiece to the Los Angeles Rams, the San Francisco 49ers and the Seattle Seahawks. One cover in the six, 15-16 at San Francisco getting 1.5. The two games against the Rams were lost by a combined 45 points.

The total

Ten of 17 went over, a rate seven teams topped and five shared: no strong lean either way.

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