Take the over 44. Indianapolis is a bet at -6.5 and a pass at -7, which is where most books have it.

Indianapolis Colts
Upcoming games
The Colts were 7-1 at the end of October 2025 and lost eight of their last nine. Colts odds paid early, 3.10 units up by the end of October, and our predictions for every Indianapolis game are above.
Two halves, one cover rate
Indianapolis finished 8-9 with 10 covers in 17 games; five NFL teams had a better cover rate and three the same one. The covers held up better than the wins: six in the first eight games, four in the last nine. They scored 27.41 points a game, a figure only seven NFL teams beat.
The wins did not hold. Seven of the first eight, then one more, 31-25 over Atlanta in Berlin laying 5.5, which covered, and seven straight losses to close.
Getting points paid against the spread
As underdogs the Colts went 2-6 straight up and 5-3 against the spread. As favorites, 6-3 and 5-4. On the road it was five covers in eight; five NFL teams did better away, four matched. At home, four covers in eight. The two longest prices they won at both came early: 29-28 over Denver at +110, and 38-24 at the Los Angeles Chargers at +120. The two shortest-price losses were both away: 20-27 at Pittsburgh at -170 and 19-36 at Jacksonville at -135.
Backing the Colts every week
September made 1.33 units and October 1.77. November lost 1.63, December 4.0 without a win, January 1.0. Over 16 priced games that is 3.53 units down, and 20 NFL teams did better. Home games finished +0.50 on seven priced; away games -4.40 on eight. The 0.17 made on eight priced games as favorites was wiped out by 3.70 lost as underdogs.
The AFC South
A sweep of the Tennessee Titans, both covered. Two losses to the Jacksonville Jaguars, neither covered. Two losses to the Houston Texans, one covered: 30-38 in Houston in the final game, getting 9.5.
The total
Nine overs and seven unders in the 16 games with a posted total; the 16-20 home loss to Houston had no total and no moneyline. No lean.
Questions and answers
When did the Colts’ 2025 season turn?
After a 31-25 win over Atlanta in Berlin on 9 November they lost their last seven games.
How often did the Colts cover the spread in 2025?
In 10 of 17 regular-season games; only five NFL teams covered more often.
What did the Colts do against the spread when getting points in 2025?
They covered five of eight, while winning only two of them.
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