Table of Contents
Week 10 of the NFL season, might start off with a whimper but it definitely finishes with a bang as we get some exciting matchups to close out the weekend.
A few of the Sunday games will see the Ravens vs, Vikings, Rams vs. 49ers with NFC West implications on the line, Bills vs. Dolphins which could be for the divisional lead, and Steelers vs. Chargers on Sunday Night Football.
The big game on Sunday, Nov. 9, is a showdown between the Detroit Lions and Washington Commanders. If you recall, the Commanders eliminated the Lions from the Playoffs last year. Week 10 closes with an exciting NFC showdown on Monday Night Football as the Green Bay Packers host the Philadelphia Eagles. One of these four teams should represent the NFC in the Super Bowl .
There are four teams on bye this week: Bengals, Cowboys, Chiefs, Titans. So, prepare your bets and fantasy football teams accordingly.
Without any further delay, let’s take a look at the NFL Week 10 odds and make our early Week 10 picks. There’s no shame in getting your Week 10 NFL bets in early as there is some value on the boards.
NFL Week 10 Schedule
Date | Time (ET) | Road Team | Home Team |
---|---|---|---|
Thursday, Nov. 6 | 8:15pm | Las Vegas Raiders | Denver Broncos |
Sunday, Nov. 9 | 9:30am | Atlanta Falcons | Indianapolis Colts |
Sunday, Nov. 9 | 1:00pm | Buffalo Bills | Miami Dolphins |
Sunday, Nov. 9 | 1:00pm | New York Giants | Chicago Bears |
Sunday, Nov. 9 | 1:00pm | Jacksonville Jaguars | Houston Texans |
Sunday, Nov. 9 | 1:00pm | Baltimore Ravens | Minnesota Vikings |
Sunday, Nov. 9 | 1:00pm | Cleveland Browns | New York Jets |
Sunday, Nov. 9 | 1:00pm | New England Patriots | Tampa Bay Buccaneers |
Sunday, Nov. 9 | 1:00pm | New Orleans Saints | Carolina Panthers |
Sunday, Nov. 9 | 4:05pm | Arizona Cardinals | Seattle Seahawks |
Sunday, Nov. 9 | 4:25pm | Los Angeles Rams | San Francisco 49ers |
Sunday, Nov. 9 | 4:25pm | Detroit Lions | Washington Commanders |
Sunday, Nov. 9 | 8:20pm | Pittsburgh Steelers | Los Angeles Chargers |
Monday, Nov. 10 | 8:15pm | Philadelphia Eagles | Green Bay Packers |
NFL Week 10 Odds
As we dive into the early Week 10 NFL odds, we find that there are some opportunities on the boards at the best sports betting sites.
Unlike most other weeks, Week 10 sees a lot of close matchups with no spread higher than 6.5 points and no moneyline higher than -285 as of this writing.
The Denver Broncos are the largest betting favorites of the week as they have a -285 moneyline and are favored by 6.5 points over the Raiders.
Just like in Week 8, the biggest road favorite is the Buffalo Bills as they’re favored by 5.5 points at Miami. The Bills have absolutely owned the Dolphins since Josh Allen came into the league.
It should come as no surprise that the highest Total of the week is 49.5 points for the Lions vs. Commanders matchup. This came should see plenty of scoring, explosive plays, and overs on many player prop bets.
With that said, check out the best handicapping membership in the industry today. Take advantage of the free trial and browse through thousands of picks for all major sports, including the NFL.
NFL Week 10 Predictions
Let’s take a look at the full slate of NFL Week 10 matchups and make our NFL picks for each game.
Las Vegas Raiders vs. Denver Broncos Odds
Team | Moneyline | Spread | Total |
---|---|---|---|
Las Vegas Raiders | +230 | +6.5 (-108) | Over 43.5 (-110) |
Denver Broncos | -285 | -6.5 (-112) | Under 43.5 (-110) |
Week 10 opens up with an AFC West clash on Thursday Night Football.
The Las Vegas Raiders went into full reset mode this offseason, and they’re hoping to make some progress in 2025. After a quarterback carousel and Davante Adams’ exit to the Jets, the Raiders prioritized experience and stability by nabbing veteran signal-caller Geno Smith. They also addressed their depleted receiving corps and backfield, drafting running back Ashton Jeanty and wideout Jack Bech while re-signing Jakobi Meyers.
The offense could still face growing pains behind a line that returns Kolton Miller and Dylan Parham but has multiple question marks. New additions like rookie guard Caleb Rogers and second-year center Jackson Powers-Johnson will be asked to contribute early.
Defensively, Las Vegas was ravaged by injuries in 2024, and this unit plunged from ninth to 25th in points allowed. If Maxx Crosby, Christian Wilkins, and Malcolm Koonce can stay healthy, this front could re-emerge as one of the best pass-rushing units in football. The loss of safety Tre’von Moehrig was a blow, but the Raiders attempted to bolster the secondary by signing Jeremy Chinn and drafting Darius Porter. Still, cornerback is a glaring concern, and the linebacker group has reset again following Robert Spillane’s departure.
The Denver Broncos are entering 2025 with continuity and momentum. Bo Nix is back at quarterback after a solid rookie year, and Sean Payton has the offense retooled with additions like tight end Evan Engram and running back J.K. Dobbins. Dobbins has a troubling injury history, but he flashed occasional form with the Chargers last season and could play a major role after incumbent Javonte Williams skipped town for Dallas. The offensive line is still a strength, with Garett Bolles and Mike McGlinchey bookending a physical front.
Las Vegas Raiders vs. Denver Broncos Predictions
The Broncos are just the better, deeper team. I expect the Raiders to improve thanks to an infusion of new blood this offseason, but I still trust Denver in the short term, especially at home.
Bet: Denver Broncos -6.5 (-112)
Atlanta Falcons vs. Indianapolis Colts Odds
Team | Moneyline | Spread | Total |
---|---|---|---|
Atlanta Falcons | -112 | -1.5 (-102) | Over 44.5 (-110) |
Indianapolis Colts | -108 | +1.5 (-118) | Under 44.5 (-110) |
This is one of the most evenly matched games of the week, and oddsmakers agree. Both teams are in the mix in their respective divisions – the Falcons in the NFC South and the Colts in the AFC South.
The Atlanta Falcons are betting on a playoff leap in 2025, and their draft strategy made it clear they’re not messing around. Trading next year’s first-rounder to go all-in on this season, Atlanta landed edge rusher Jalon Walker at No. 15 and followed it up with fellow defensive studs James Pearce and Xavier Watts. If those three guys hit even close to expectations, this front seven could cause real problems. Add in the momentum from quarterback Michael Penix Jr.’s late-season surge, and there’s real reason for excitement in Atlanta.
The Indianapolis Colts took a more balanced approach, prioritizing protection and pass-catching for Anthony Richardson and Daniel Jones. Stealing tight end Tyler Warren at No. 14 was a win for a team lacking weapons over the middle. The Colts also added depth on defense with J.T. Tuimoloau and Justin Walley, addressing their secondary and pass rush. If their quarterbacks can just be average, this roster has the bones of a Wild Card contender.
Atlanta Falcons vs. Indianapolis Colts Predictions
The biggest difference between these two teams? Ceiling. The Falcons added legit difference-makers on defense, and if their offense can even be league-average, this team could run away with the NFC South. The Colts might be deeper overall, but they don’t have the same breakout potential.
Bet: Atlanta Falcons -1.5 (-102)
Buffalo Bills vs. Miami Dolphins Odds
Team | Moneyline | Spread | Total |
---|---|---|---|
Buffalo Bills | -225 | -4.5 (-110) | Over 46.5 (-110) |
Miami Dolphins | +185 | +4.5 (-110) | Under 46.5 (-110) |
The Miami Dolphins spent their draft loading up in the trenches, which was a smart move given their offensive line was one of the league’s worst in 2024. They used four picks on linemen, including their first three selections. Kenneth Grant brings size and disruption to the defensive interior, while Jonah Savaiinaea should plug a massive hole left by Terron Armstead’s retirement. The team also rolled the dice on quarterback Quinn Ewers in the seventh round, insurance for yet another uncertain year with the injury-prone Tua Tagovailoa.
The Dolphins still have glaring holes, though. Their secondary is a major concern, and their choice to pass on key positions in favor of depth at running back and safety raised eyebrows. Miami has the firepower to hang with anyone when healthy, but with so many question marks on both sides of the ball, this roster still feels like it’s stuck in limbo.
The Buffalo Bills, on the other hand, are looking to make the leap from contender to champion. They used their first five picks on the defensive line and secondary, making it clear they’re preparing to finally take down Kansas City. Maxwell Hairston adds length and speed at cornerback, while T.J. Sanders, Landon Jackson, and Deone Walker give the Bills three new weapons to support newcomer Joey Bosa up front. This unit could be terrifying by December.
Buffalo Bills vs. Miami Dolphins Predictions
The Dolphins have made strides, but the Bills are loaded, healthy, and hungry. Until Miami proves it can protect its quarterback or stop elite passing offenses, we’re backing the more complete team.
Bet: Buffalo Bills -4.5 (-110)
New York Giants vs. Chicago Bears Odds
Team | Moneyline | Spread | Total |
---|---|---|---|
New York Giants | +180 | +4 (-110) | Over 40.5 (-110) |
Chicago Bears | -218 | -4 (-110) | Under 40.5 (-110) |
The Chicago Bears added a wealth of talent in the draft to support quarterback Caleb Williams, including wide receiver Luther Burden and offensive tackle Ozzy Trapilo. While the selection of tight end Colston Loveland raised some eyebrows, the Bears made up for it with strong Day 2 picks. They also addressed defense with Shemar Turner and Ruben Hyppolite. It wasn’t a perfect draft, but the support system for Williams looks much improved.
It’ll also be fascinating to see how the team is transformed under first-year head coach Ben Johnson, who comes over after enjoying a ton of success running the Detroit Lions’ offense over the past couple of years. He can’t be any worse than Matt Eberflus…right!?
The New York Giants also had a solid draft but drew criticism for reaching on quarterback Jaxson Dart in the first round. Still, surrounding that move were excellent selections like edge rusher Abdul Carter, interior lineman Marcus Mbow, and do-it-all running back Cam Skattebo. New York addressed the trenches and backfield with value across the board.
New York Giants vs. Chicago Bears Predictions
Both teams are hoping their young quarterbacks make a leap, but Chicago’s supporting cast looks stronger, especially on the offensive line. The Giants may have long-term upside, but this year, they’re still sorting things out.
Bet: Chicago Bears -4 (-110)
Jacksonville Jaguars vs. Houston Texans Odds
Team | Moneyline | Spread | Total |
---|---|---|---|
Jacksonville Jaguars | +145 | +3.5 (-110) | Over 44 (-110) |
Houston Texans | -175 | -3.5 (-110) | Under 44 (-110) |
The Jacksonville Jaguars pulled off a blockbuster move to trade up for Travis Hunter at No. 2 overall. That was a bold swing, especially for a team that didn’t address its most glaring issue: the offensive line. Hunter’s ability to play both wide receiver and cornerback is exciting, but giving up a first- and second-rounder for a non-quarterback felt desperate. Jacksonville’s defense has been among the league’s worst, so adding Hunter and Caleb Ransaw does help, but Trevor Lawrence might not survive another season behind a leaky front if Wyatt Milum is their only real line upgrade.
The Houston Texans had one job: protect C.J. Stroud. Instead, the Texans passed on offensive linemen in favor of adding multiple receivers and a couple of defenders. Trading out of the first round felt like a punt, though they did land a steal in Aironatae Ersery in Round 2. He may have to be an instant starter with Laremy Tunsil gone. Jayden Higgins and Jaylin Noel bring size and athleticism to a depleted receiving corps, but the lack of protection up front could catch up to this offense quickly, especially with Stefon Diggs gone and Tank Dell banged up.
Jacksonville Jaguars vs. Houston Texans Predictions
Both teams showed flashes in the draft. Jacksonville with some Day 3 gems like Jonah Monheim, and Houston with value picks like Ersery, but neither franchise fully addressed its core needs. The Jaguars loaded up on versatility and potential, while the Texans walked away with a crowded WR room and a bunch of “maybe” defenders. Expect plenty of volatility from both of these rosters as the season progresses.
With question marks on both sides and two struggling offensive lines, the safer play is to back the better quarterback with a more stable coaching staff. C.J. Stroud gives Houston a tangible edge, especially at home.
Bet: Houston Texans -3.5 (-110)
Baltimore Ravens vs. Minnesota Vikings Odds
Team | Moneyline | Spread | Total |
---|---|---|---|
Baltimore Ravens | -185 | -4 (-110) | Over 42.5 (-110) |
Minnesota Vikings | +154 | +4 (-110) | Under 42.5 (-110) |
If the Minnesota Vikings entered the 2025 NFL Draft with a shopping list, they didn’t need many items. Just four picks, to be exact. But they used those picks wisely. Donovan Jackson might not be the flashiest name, but he fits Kevin O’Connell’s plan to build the best offensive line in football. Pairing him with offseason signings Ryan Kelly and Will Fries gives Minnesota a rock-solid interior. Add in defensive tackle Tyrion Ingram-Dawkins – one of the steals of Day 3 – and the Vikings may have done more with four picks than some teams did with ten.
The Baltimore Ravens did what the Ravens always seem to do: win the draft. Malaki Starks at No. 27? Ridiculous value. Mike Green in the second round despite first-round talent? Stolen. Emery Jones adding depth to the offensive line? Smart. And that’s before we even get to Carson Vinson, a small-school project with big-time upside. Baltimore’s draft haul earned glowing reviews across the board, and it’s hard to argue with a front office that seems to pull rabbits out of hats every April.
Baltimore Ravens vs. Minnesota Vikings Predictions
On the field, this sets up as a classic power vs. power matchup. The Vikings will try to win in the trenches and control the tempo, while the Ravens will be looking to unleash their new-look pass rush and capitalize on Minnesota’s lack of wide receiver depth. Lamar Jackson is the X-factor. His mobility will be a problem for a Minnesota defense that didn’t invest heavily in speed at linebacker or safety.
The Vikings are always tough, but Baltimore’s revamped defense and elite draft class give them a slight edge.
Bet: Baltimore Ravens -4 (-110)
Cleveland Browns vs. New York Jets Odds
Team | Moneyline | Spread | Total |
---|---|---|---|
Cleveland Browns | +114 | +2.5 (-110) | Over 39.5 (-110) |
New York Jets | -135 | -2.5 (-110) | Under 39.5 (-110) |
This one could be ugly. The Cleveland Browns are coming off a 6–11 season that featured three different starting quarterbacks, none of whom looked like long-term answers. In the draft, they passed on Shedeur Sanders early but still wound up landing him late…just a few picks after they drafted another QB, Dillon Gabriel.
Mason Graham, their top pick, should help solidify the defensive line, and Quinshon Judkins brings power to a backfield that needed fresh legs. Still, the overall roster feels like it’s stuck in the mud. They’re good enough to be annoying, but not good enough to win consistently.
The New York Jets weren’t much better in 2024, finishing 5–12, but they’ve at least chosen a direction. Armand Membou looks like a building block on the offensive line, and the additions of Arian Smith and Mason Taylor give the offense some juice. Defensively, this unit has real potential, especially in the secondary, where Malachi Moore and Azareye’h Thomas add playmaking to a group that already includes Sauce Gardner. The Jets also signed Justin Fields, who should give them a lot more juice at QB than Aaron Rodgers did in his lone disastrous season in town.
Cleveland Browns vs. New York Jets Predictions
The wild card here is who’s starting at QB for the Browns by the time this game rolls around. If Sanders plays and performs even reasonably well, Cleveland has a shot. But if it’s another season of quarterback rotation roulette, the edge swings back to New York. The Jets don’t do anything flashy, but they’re less chaotic right now, and that might be enough.
Bet: New York Jets -2.5 (-110)
New England Patriots vs. Tampa Bay Buccaneers Odds
Team | Moneyline | Spread | Total |
---|---|---|---|
New England Patriots | +170 | +4.5 (-110) | Over 41.5 (-110) |
Tampa Bay Buccaneers | -205 | -4.5 (-110) | Under 41.5 (-110) |
This Week 10 clash pits two franchises in transition, but on very different timelines. The Tampa Bay Bucs are coming off a surprise 9–8 season that ended in a playoff berth and a Wild Card loss, while the Patriots limped to the finish line at 4–13 and handed the keys to new head coach Mike Vrabel.
Tampa Bay kept its core intact this offseason, re-signing Baker Mayfield and continuing to build around him. With Mike Evans still producing and Chris Godwin healthy again, the offense has a real chance to build on last year’s flashes. First-round pick Emeka Egbuka adds another weapon, and the offensive line – anchored by All-Pro tackle Tristan Wirfs – looks improved. On defense, they beefed up the secondary and added depth at linebacker, hoping to finally shed the inconsistency that’s plagued them the past two years.
The New England Patriots are starting over, but not from scratch. Vrabel has brought new energy to Foxborough, and the Patriots were aggressive on both sides of the ball this offseason. They rebuilt the offensive line, added weapons like TreVeyon Henderson in the backfield, and signed veterans who fit Vrabel’s no-nonsense identity. On defense, the Pats are banking on the growth of Christian Gonzalez and a healthier Christian Barmore to stabilize a group that collapsed down the stretch in 2024.
New England Patriots vs. Tampa Bay Buccaneers Predictions
This isn’t quite a tank job for New England, but it’s definitely a reset. The Bucs, on the other hand, still have playoff aspirations in a weak NFC South and should be favored at home in this one. The talent gap isn’t enormous, but the cohesion edge clearly belongs to Tampa.
Bet: Tampa Bay Buccaneers -4.5 (-110)
New Orleans Saints vs. Carolina Panthers Odds
Team | Moneyline | Spread | Total |
---|---|---|---|
New Orleans Saints | +154 | +3 (-110) | Over 40.5 (-110) |
Carolina Panthers | -185 | -3 (-110) | Under 40.5 (-110) |
Both the New Orleans Saints and Carolina Panthers finished 5–12 in 2024, and both enter 2025 with limited expectations. The Saints finally moved on from Derek Carr this offseason and drafted Tyler Shough out of Louisville to potentially lead the charge. Kellen Moore takes over as head coach, and while Shough isn’t locked in as the starter, he has the tools to push for the job quickly. With Alvin Kamara returning to form late last year and young talent like Kelvin Banks Jr. added to the offensive line, there’s reason for cautious optimism in New Orleans.
The Panthers, meanwhile, are still waiting on Bryce Young to deliver on his draft-day promise. He showed flashes of growth at the end of last season, but the results remain underwhelming overall. To support him, the Panthers brought in wideout Tetairoa McMillan and overhauled parts of their offensive line. Still, this offense ranked near the bottom of the league in most major categories last year, and until Young proves otherwise, expectations are muted.
New Orleans Saints vs. Carolina Panthers Predictions
Defensively, both teams have a few legitimate pieces. New Orleans still has playmakers in the front seven and could be stingy if healthy, while Carolina leans on Derrick Brown, Jaycee Horn, and new additions like veteran linebacker Josey Jewell. The Panthers were sneaky solid against the run in 2024, and they’ll look to pressure Shough early and often in what figures to be a low-scoring battle.
This could be a rock fight. Neither offense feels particularly trustworthy, and both squads are still figuring things out under new leadership. If Shough shows poise and can manage the game, the Saints have a path to victory. But if Young is even modestly improved, Carolina’s continuity and home crowd might be just enough to get them over the line.
Bet: Carolina Panthers (-185)
Arizona Cardinals vs. Seattle Seahawks Odds
Team | Moneyline | Spread | Total |
---|---|---|---|
Arizona Cardinals | +100 | +1.5 (-110) | Over 42.5 (-110) |
Seattle Seahawks | -120 | -1.5 (-110) | Under 42.5 (-110) |
The Seattle Seahawks went 8–9 in 2024 and missed the playoffs, but expectations are higher in Year 2 under Mike Macdonald. The defense showed real growth late last season, and the Seahawks used the offseason to retool the offense around new quarterback Sam Darnold. He’ll be throwing to a new group of wideouts that includes Jaxon Smith-Njigba and free-agent addition Cooper Kupp, assuming Kupp can stay on the field. Seattle also traded DK Metcalf to the Steelers and lost Tyler Lockett in free agency, and it’ll be fascinating to see whether JSN can finally step into a WR1-type of role.
The Arizona Cardinals aren’t far behind in terms of roster talent, but they’re still waiting for it all to click. Arizona went 7–10 in 2024 and has leaned into continuity, bringing back most of the offense from last year. Kyler Murray’s knee should finally be fully healthy, and the connection with Marvin Harrison Jr. remains the x-factor. The Cards also return James Conner in the backfield and Trey McBride at tight end, both of whom give Murray reliable security blankets in the short game.
Arizona’s defense might be the most improved unit on the field this week. Josh Sweat headlines a revamped front seven that also includes Calais Campbell, Walter Nolen, and Darius Robinson. That group could give Seattle’s retooled offensive line some serious problems, especially if Kupp isn’t 100%. But Seattle’s own defense isn’t a pushover, with Leonard Williams and a ball-hawking secondary that includes Devon Witherspoon and Tariq Woolen ready to clamp down.
Arizona Cardinals vs. Seattle Seahawks Predictions
Ultimately, this is a true toss-up. If Darnold plays clean and gets the ball out quickly, Seattle has the edge in overall depth and coaching. But if Murray finds rhythm and Arizona’s pass rush shows up, this could be the game that finally announces the Cardinals as legit threats in the NFC West.
Bet: Arizona Cardinals +1.5 (-110)
Los Angeles Rams vs. San Francisco 49ers Odds
Team | Moneyline | Spread | Total |
---|---|---|---|
Los Angeles Rams | +102 | +2 (-110) | Over 44 (-110) |
San Francisco 49ers | -122 | -2 (-110) | Under 44 (-110) |
This matchup might look a little different than in past years, but it still matters. The San Francisco 49ers collapsed to a 6–11 record last season after injuries wiped out a good chunk of their offense, including Brandon Aiyuk and Christian McCaffrey. Both are back and mostly healthy to start 2025, though Aiyuk may miss Week 1. Brock Purdy has shown flashes of brilliance when given time to operate. The offensive line isn’t perfect, but there’s enough continuity to believe in a bounce-back.
The Los Angeles Rams rebounded from a sluggish start in 2024 to go 9–8 and grab a Wild Card spot. Matthew Stafford is still slinging it, though his favorite weapon, Cooper Kupp, is now in Seattle. LA is hoping fellow veteran Davante Adams still has something left in the tank. Blake Corum brings fresh legs to a crowded backfield, while the offensive line has been quietly reinforced. They’ll need to be sharp early, because San Francisco’s pass rush is no joke.
Defensively, the Rams will look to rising star Kobie Turner to anchor the line after a breakout 2024. But they’ll need more consistency on the back end, especially if Purdy and the 49ers find rhythm in the play-action game. San Francisco’s defense also gets a boost with a healthy Dre Greenlaw and a deep front four that could create havoc for Stafford in the pocket.
Los Angeles Rams vs. San Francisco 49ers Predictions
This one could swing either way, especially given the recent injury history on both sides. If McCaffrey stays on the field and the 49ers avoid early breakdowns, they have the edge. But the Rams at home are a different beast, and Stafford has shown he can still lead clutch drives in big moments.
Bet: Los Angeles Rams +2 (-110)
Detroit Lions vs. Washington Commanders Odds
Team | Moneyline | Spread | Total |
---|---|---|---|
Detroit Lions | +102 | +1.5 (-110) | Over 45 (-110) |
Washington Commanders | -122 | -1.5 (-110) | Under 45 (-110) |
The Detroit Lions were banged up for much of 2024 but still finished with the league’s best record. A 15–2 record, the No. 1 seed, and an NFC title game appearance validated the Dan Campbell blueprint, and now they return 20 of 22 starters, including MVP finalist Jared Goff and All-Pro wideout Amon-Ra St. Brown.
With Jameson Williams, Jahmyr Gibbs, and Sam LaPorta all taking major steps last year, Detroit brings back one of the league’s most explosive offenses. And if their revamped interior O-line holds up, there might not be many teams capable of slowing them down.
The Washington Commanders made the biggest leap of any NFC team in 2024. Rookie QB Jayden Daniels lit the league on fire, winning 12 games and leading the Commanders to the NFC Championship.
The front office doubled down on their offensive overhaul this spring, trading for Pro Bowl LT Laremy Tunsil and drafting another future starter in Josh Conerly Jr. They also added Deebo Samuel to pair with Terry McLaurin, giving Daniels a legit 1-2 punch on the perimeter.
It’s not all sunshine, of course. Washington’s defense took some hits, and their secondary is a question mark against elite passing teams. That’s a dangerous combination against Goff and the Lions, especially with Detroit’s tendency to dictate tempo early and bury teams with their scripted offense. Still, if Daniels continues his rocket ascent, the Commanders have the firepower to hang in any shootout.
Detroit Lions vs. Washington Commanders Predictions
This game could be a sneaky preview of a future Playoff rematch. The Lions are more polished, deeper, and further along in their championship arc, but Washington is rising fast. In a neutral setting this might be a toss-up, but in Detroit, it’s hard to go against Goff and that crowd.
Bet: Detroit Lions -1.5 (-110)
Pittsburgh Steelers vs. Los Angeles Chargers Odds
Team | Moneyline | Spread | Total |
---|---|---|---|
Pittsburgh Steelers | +164 | +4.5 (-110) | Over 42.5 (-110) |
Los Angeles Chargers | -198 | -4.5 (-110) | Under 42.5 (-110) |
Two playoff teams from last season meet in what could be a defensive slugfest with a dash of star power. The Pittsburgh Steelers made one of the boldest moves of the offseason by signing Aaron Rodgers, who returns from a dreadful season in New York at age 41 to try and lift the Steelers out of their offensive funk. His arm strength isn’t what it once was, but behind an improved offensive line and with a shiny new toy in DK Metcalf, the Steelers believe they’ve given him just enough to make it work.
The Los Angeles Chargers were one of 2024’s best surprises, rebounding from a 5–12 finish the year prior to win 11 games and secure a playoff spot. Jim Harbaugh’s arrival changed everything, bringing a toughness and efficiency that fit the roster. Justin Herbert returns after playing hurt most of last year, and he’ll be aided by a deeper WR room that includes Ladd McConkey and second-rounder Malachi Corley. The offense may not be explosive, but it’s sturdy and methodical.
Defensively, both teams are built to hit. Pittsburgh still leans heavily on T.J. Watt and Minkah Fitzpatrick, and their cornerback additions give them more versatility than they’ve had in years. The Chargers are retooling up front after injuries hit hard last year, but Derwin James and Troy Dye form a scary spine if they’re on the field. With both teams bringing real pass rush, this one might turn into a grind-it-out affair decided in the trenches.
Pittsburgh Steelers vs. Los Angeles Chargers Predictions
Rodgers’ health remains a wild card, and the Chargers are the more complete team right now. But Harbaugh’s group still has something to prove, especially against a franchise like Pittsburgh. If the Steelers keep Rodgers upright and limit turnovers, they can absolutely win. But the safer Week 1 play is trusting Herbert and a more cohesive L.A. squad at home.
Bet: Los Angeles Chargers -4.5 (-110)
Philadelphia Eagles vs. Green Bay Packers Odds
Team | Moneyline | Spread | Total |
---|---|---|---|
Philadelphia Eagles | -120 | -1.5 (-110) | Over 45.5 (-110) |
Green Bay Packers | +100 | +1.5 (-110) | Under 45.5 (-110) |
Green Bay enters this one with something to prove. Despite back-to-back playoff appearances, the Green Bay Packers have struggled to take that next step, exiting early each time. Quarterback Jordan Love showed flashes but also inconsistency, and the team doubled down on its identity this offseason. If Love can take a step forward and avoid the mobility issues that plagued him early in 2024, Green Bay could surprise people.
The Philadelphia Eagles, on the other hand, are riding high after their Super Bowl 59 win last February, and the expectations couldn’t be higher. Jalen Hurts returns to a stacked offense with A.J. Brown, DeVonta Smith, Dallas Goedert, and a deep backfield that now includes A.J. Dillon and Will Shipley to complement the great Saquon Barkley. They’ll also benefit from a healthy offensive line and new OC Kevin Patullo, who’s expected to keep emphasizing the run game while giving Hurts room to stretch the field.
Philadelphia Eagles vs. Green Bay Packers Predictions
Both defenses should have something to say in this one. The Packers’ pass rush, led by Rashan Gary and Devonte Wyatt, added more youth in the draft and continues to be disruptive up front. Meanwhile, Philadelphia’s defense might be even scarier. Jalen Carter is flanked by Nakobe Dean, Jordan Davis, and veteran additions like Azeez Ojulari and Zach Baun. It’s a front designed to live in the backfield.
This has all the makings of a playoff preview. Green Bay wants to grind things out and limit possessions. Philly wants to test secondaries and pin its ears back on defense. If Love isn’t sharp, this could get away from the Packers quickly. But if he manages the game well and Jacobs churns out tough yards, Green Bay has a shot to hang around.
Bet: Philadelphia Eagles -1.5 (-110)
NFL Week 10 Best Bets
Check out our best NFL bets for Week 10:
- Jets -2.5 (-110) vs. Browns
- Buccaneers -4.5 (-110) vs. Patriots
- Eagles -1.5 (-110) vs. Packers
We’re backing the Jets to win a game of controlled chaos against a Browns team with a wildly unpredictable QB situation. Tampa Bay brings back most of a playoff roster and should take care of business at home against a rebuilding Patriots squad. And in a potential NFC playoff preview, I have a hard time going against the Birds at home in primetime.
If you combine all three of these best bets into an NFL parlay, then you would win $596 on a $100 wager.