Baltimore Orioles vs New York Yankees Picks and Predictions April 28th 2025

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Orioles Limp Home to Face Rival Yankees

After a bruising road trip, the Baltimore Orioles are desperate for a turnaround as they return to Camden Yards to host the division-leading New York Yankees. Monday night’s matchup opens a critical three-game series where Baltimore hopes to shake off a 1-5 stretch and rediscover the form they showed early in the season.

Orioles Searching for Answers After Disappointing Road Trip

Baltimore’s offense has been sputtering for over a week, scoring no more than three runs in their last seven games. Sunday’s 7-0 shutout loss to the Detroit Tigers was the latest example, where the Orioles managed just five singles and struck out 15 times.

In addition to the offensive drought, injuries have mounted. Catcher Adley Rutschman, outfielder Cedric Mullins, and infielder Jordan Westburg all sat out Sunday’s game and are considered day-to-day. Manager Brandon Hyde emphasized the challenge ahead, admitting, “We’re not playing the best baseball and we’re walking too many guys.”

The Orioles’ starting pitching has been unable to carry the load either. Walks and missed locations have haunted Baltimore’s arms, making it difficult to stay competitive even when opponents are not overpowering.

According to updated insights on the MLB Picks, Baltimore has covered the spread in only four of its last 13 games, underlining the depth of their recent struggles.

Tomoyuki Sugano Offers a Glimmer of Hope on the Mound

Despite Baltimore’s difficulties, Monday’s starting pitcher provides a reason for optimism. Tomoyuki Sugano (2-1, 3.54 ERA) will make his sixth career MLB start and has thrown at least seven innings in each of his past two outings. The right-hander from Japan has proven durable and efficient, qualities the Orioles desperately need right now.

Sugano will have to be sharp against a Yankees lineup that ranks top-five in home runs. He has also given up a homer in four straight appearances, an alarming trend he will need to reverse against New York’s power hitters.

The MLB Scores and Odds reveal that games involving Sugano have typically hit the under, suggesting that if Baltimore is to prevail, it will likely be a low-scoring affair.

Yankees Bringing Power and Momentum to Camden Yards

Meanwhile, the New York Yankees arrive in Baltimore with confidence after sweeping the Toronto Blue Jays in a Sunday doubleheader. Fresh off an 11-2 and 5-1 pair of wins, the Yankees are riding a hot streak, winning five of their last seven games.

Backup catcher JC Escarra provided an emotional highlight on Sunday by belting his first career home run at age 30, a feel-good moment that lit up the clubhouse. Manager Aaron Boone remarked after the victory, “Really excited for JC and he did a great job behind the plate, too.”

New York will send rookie right-hander Will Warren (1-0, 4.79 ERA) to the mound for the series opener. Warren has shown flashes of potential but remains largely untested against AL East opponents. Monday night will mark his first career appearance against the Orioles.

Fans and bettors are noticing, too. The Yankees have been one of the most reliable teams for MLB Betting Experts over the past two weeks, consistently outperforming expectations on both offense and the mound.

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Key Factors That Could Decide the Series Opener

Will the Orioles’ offense wake up?

Baltimore has struggled mightily to string hits together, and with several regulars potentially sidelined, the challenge grows even greater. They’ll need Rutschman or Mullins back — or unexpected heroics from elsewhere in the lineup — to generate offense.

Can Sugano silence the Yankees’ bats?

Sugano’s ability to avoid home runs and limit traffic on the bases could dictate the entire game. His pinpoint command will be tested by an aggressive Yankees team that feasts on mistakes.

Will New York’s young pitching hold?

Warren has yet to face a lineup like Baltimore’s when healthy, so if the Orioles find early success, it could tilt momentum in their favor. Warren’s ability to command his secondary pitches will be key.

Betting Angle to Consider

The Orioles’ cold bats combined with Sugano’s efficient style could favor another low-scoring game. However, given the Yankees’ firepower, a team totals prop favoring New York might also hold value.

A baseball player in an Orioles uniform gestures confidently while celebrating a play-

Final Thoughts

The Orioles are desperate, the Yankees are surging. Monday’s series opener will reveal whether Baltimore can stabilize and start to climb back toward contention — or if their early-season slump is the beginning of a deeper slide.

Sugano offers a fighting chance, but if the Orioles’ offense can’t capitalize against a rookie starter, Baltimore’s struggles may only deepen.

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Mike uses his strong sports knowledge to analyze all the angles to find the most profitable wagers. Iron Mike handicaps MLB, college football, NFL, NBA, and NCAA basketball. I'm an actual sports and gambling junkie!

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