Week 11 of the 2025-26 NFL season opens with and AFC East clash as the New England Patriots host the New York Jets on  Thursday Night Football.

Sunday’s slate of action features the final International Game pf the year, as the Miami Dolphins and Washington Commanders battle in Madrid, Spain. This means that NFL bettors will have to get up super early for this matchup.

Later in the day, there are a handful of games that have us excited for Week 11 including: the Buccaneers vs. Bills, Bengals vs. Steelers, Bears vs. Vikings, and Chiefs vs. Broncos.

However, the main event for Week 11 is the Sunday Night Football game where the Philadelphia Eagles host the Detroit Lions. Could this be an early NFC Championship preview where the winner becomes the Super Bowl favorite?

Unlike in Week 8, where there were six teams on bye, Week 11 will only feature two NFL teams on a bye: Colts and Saints.

Without any further delay, let’s take a look at the NFL Week 11 odds and make our early Week 11 picks. There’s no shame in getting your Week 11 NFL bets in early as there is some value on the boards.

NFL Week 11 Schedule

NFL Week 11 Odds

As we dive into the early Week 11 NFL odds, there are some notable betting lines that jump off the page at the best sports betting sites.

The Cowboys vs. Raiders have the highest Total for the Week at 50.5 points. However, there are a handful of games that range between 48.5 and 49.5 total points. You definitely want to pay attention to the weather for this weekend due to the seasons changing on the East Coast. Also, don’t forget to check out our top player prop bets of the week, as well.

The Patriots are the biggest favorite of the week as they check in at -800 odds and favored by 11.5 points over the Jets. There are several games with spreads above the touchdown mark, which makes shopping for Underdogs a bit more challenging.

With that said, check out the industry’s best handicapping membership for elite NFL picks all season long. Sign up today and enjoy a free trial to thousands of picks from all major sports.

Score on Every NFL Bet
With Our Elite

Handicapping Membership!

Get Free Trial

NFL Week 11 Predictions

Let’s take a look at the full slate of NFL Week 11 matchups and make our NFL picks for each game.

New York Jets vs. New England Patriots Odds

The New England Patriots return home for Thursday Night Football riding 7-game winning streak and looking every bit like an AFC contender as they are at the top of the AFC East division. Drake Maye has continued his steady ascent, throwing for 270 yards and two touchdowns in last week’s 28–23 win over Tampa Bay.

Even with a pair of interceptions, Maye’s command of the offense stood out — targeting Mack Hollins (6 catches, 106 yards) and Kyle Williams (72 yards, 1 TD) for chunk plays while balancing the attack through the ground game. The Patriots rushed for 166 yards as TreVeyon Henderson exploded for 147 and two scores, setting a punishing tone that mirrored New England’s dominance in the trenches.

The New York Jets, meanwhile, enter off one of their most complete outings of the season — a 27–20 win over the Browns that snapped their losing streak. Justin Fields threw a touchdown to Breece Hall, and the two combined for 111 of the team’s 127 rushing yards.

Hall was again the engine, averaging 4.0 yards per carry and contributing a 42-yard touchdown reception — the longest play of the game. New York’s defense also stiffened late, holding Cleveland to 10 points over the final two quarters despite Dillon Gabriel and Quinshon Judkins moving the ball efficiently on the ground.

For the Patriots, the challenge lies in maintaining focus after a statement win. New England’s offense has now scored 28 or more points in three of its last four games, and the defense has quietly improved its takeaways while limiting explosive runs. That balance has fueled the team’s 8–2 record and positioned them as road favorites most weeks. On a short turnaround, expect TreVeyon Henderson to again be featured early and often behind a confident offensive line that paved the way for over six yards per carry against Tampa Bay.

The Jets will lean on the same formula that worked against Cleveland — feed Breece Hall, keep Justin Fields on schedule, and avoid the turnovers that have doomed their season. Hall’s big-play potential gives New York a puncher’s chance, but matching Maye’s aerial production and New England’s offensive efficiency remains a tall order. The Patriots have outgained four straight opponents and boast the deeper roster on both lines of scrimmage. Unless the Jets can replicate last week’s defensive discipline and force Maye into mistakes, New England should stay in control and extend its winning streak under the primetime lights.

New York Jets vs. New England Patriots Predictions

• Spread: Jets +11.5 (-110) — New England has been dominant, but the Jets have quietly kept games tight, with five of their seven losses coming by single digits. If Breece Hall can break a few chunk runs and Justin Fields limits turnovers, New York can stay within the number even against an elite defense.
• Total: Over 43.5 (-110) — Both teams have trended higher-scoring recently. The Jets have seen the over hit in 12 of their last 16 games, while New England’s offense has topped 28 points in three of its past four. With Drake Maye dealing and TreVeyon Henderson emerging as a legitimate big-play threat, the Patriots are more than capable of holding up their end.
• Moneyline: Patriots (-800) — The Patriots are rolling behind Maye’s confident command and a run game averaging over six yards per carry last week. The Jets’ defense could cause problems, but New England’s efficiency on both sides makes an outright upset unlikely.

Bet: Patriots ML (-800), Jets +11.5 (-110), Over 43.5 (-110)

Washington Commanders vs. Miami Dolphins Odds

The Washington Commanders head to Madrid to face the Miami Dolphins in the Week 11 international matchup — a battle of two 3–7 teams with wildly different Week 10 trajectories. Washington fell 44–22 to the Lions, while Miami handled the Bills 30–13 behind its most complete effort since early October. Both squads enter with clear offensive identities: Washington leans on Marcus Mariota’s efficiency and quick rhythm, while Miami continues to be powered by explosive speed and ground dominance from De’Von Achane.

Washington’s Week 10 loss was less about offensive failure and more about defensive collapse. Mariota completed 16 of 22 passes for 213 yards and two touchdowns without a pick, spreading the ball around to Zach Ertz, Treylon Burks, and Deebo Samuel. The Commanders still moved the ball well, totaling 306 yards of offense and scoring in every quarter. But their defense was torched for 320 passing yards and 226 rushing yards — including two long touchdowns from Detroit’s Jahmyr Gibbs. The lack of containment at the edges remains a glaring concern, and unless the front seven tightens up, Miami’s speed will create similar problems.

The Dolphins flipped the script against Buffalo by dominating both lines of scrimmage. Tua Tagovailoa threw for 173 yards and two touchdowns, but it was De’Von Achane who stole the show, rushing for 174 yards on 22 carries with a 59-yard breakaway. Miami’s offense looked balanced and efficient, scoring 30 points without allowing a sack. Jaylen Waddle added 84 yards and a touchdown, while Greg Dulcich and Malik Washington provided timely secondary production. Even with two interceptions from Tagovailoa, Miami’s overall control of tempo and field position underscored a return to the fast, efficient execution that defines its best stretches.

Washington’s offense continues to show flashes of balance but lacks explosive punch to trade scores with Miami. If Jeremy McNichols and Chris Rodriguez Jr. can give Mariota steady early-down yardage, the Commanders can at least shorten the game and keep Miami’s offense on the sideline. That said, the Dolphins’ front, led by Bradley Chubb, is built to disrupt rhythm throws and force Mariota off his spot. Unless Washington’s defense finds a way to contain Achane’s burst — something few have managed — Miami’s vertical and ground efficiency should prove too much overseas.

Washington Commanders vs. Miami Dolphins Predictions

• Spread: Dolphins -2.5 (-115) — Washington has shown flashes of competence, but allowing 44 points and 546 total yards to Detroit last week raises serious red flags. Miami just gashed Buffalo for nearly 200 rushing yards, and that speed edge travels well.
• Total: Over 47.5 (-112) — Both defenses are trending in the wrong direction. The Commanders have surrendered 27+ points in four straight, while Miami has topped 30 in consecutive games. Expect fireworks in Spain.
• Moneyline: Dolphins (-148) — Tua Tagovailoa and De’Von Achane form one of the league’s most efficient duos, and the Commanders’ defense doesn’t have the personnel to contain them across four quarters.

Bet: Dolphins ML (-148), Dolphins -2.5 (-115), Over 47.5 (-112)

Tampa Bay Buccaneers vs. Buffalo Bills Odds

A non-conference matchup between the Tampa Bay Buccaneers and Buffalo Bills headlines Sunday’s early slate, as both teams try to rebound from uneven Week 10 showings. Tampa Bay’s offense put up 23 points in a narrow loss to New England, while Buffalo’s high-powered attack stalled in a 30–13 defeat at Miami. The contrast here is clear — the Buccaneers are leaning on veteran efficiency and clean execution from Baker Mayfield, while the Bills are desperate to rediscover balance and red-zone rhythm after back-to-back sluggish starts.

Tampa Bay’s loss to the Patriots wasn’t without positives. Mayfield threw three touchdowns and 273 yards, efficiently distributing to Emeka Egbuka, who exploded for 115 yards and a score on six receptions. Tight end Cade Otton and wideout Tez Johnson also chipped in a combined 124 yards and three touchdowns, proving this passing game can still stretch defenses vertically. On the ground, Sean Tucker and Rachaad White combined for 91 yards, but the Bucs struggled to convert short-yardage runs — something that could be tested again versus Buffalo’s aggressive front.

For Buffalo, the issues stemmed from inconsistency and lack of finish. Josh Allen threw for 306 yards and two touchdowns against Miami but was pressured throughout, taking three sacks and seeing drives stall in scoring range. The rushing game produced just 87 yards, with James Cook III the lone bright spot (53 yards on 13 carries). Khalil Shakir caught seven passes but averaged only 8.3 yards per grab, underscoring how Buffalo’s offense has drifted away from its big-play identity. The defense, typically reliable, couldn’t contain Miami’s ground attack and now faces another challenge against Tampa Bay’s precise short-passing rhythm.

Both sides have reasons for urgency. Tampa Bay’s offensive confidence is trending upward behind Mayfield’s quick decision-making and emerging chemistry with Egbuka, while Buffalo’s defensive line must reassert control after allowing 197 rushing yards a week ago. If the Bills can reclaim balance and limit turnovers, they remain the better overall roster, but Tampa Bay’s passing versatility gives them an edge in keeping it close on the road.

Tampa Bay Buccaneers vs. Buffalo Bills Predictions

• Spread: Bills -6.5 (−110) — Buffalo’s superior defense and bounce-back motivation should eventually separate them, but Tampa Bay’s passing precision could keep it competitive early.
• Total: Under 48.5 (-112) — Both teams are coming off physical matchups and may lean run-heavy early to settle their offenses. Expect fewer chunk plays than usual.
• Moneyline: Bills (-245) — Josh Allen should rebound with cleaner red-zone execution at home, and the defense’s depth up front is still a key difference-maker.

Bet: Bills ML (−245), Bills −6.5 (−110), Under 48.5 (−112)

Houston Texans vs. Tennessee Titans Odds

The Houston Texans return home after a statement 36–29 win over Jacksonville, while the Tennessee Titans come off their bye week following a competitive 27–20 loss to the Chargers in Week 9. Houston is suddenly back in the AFC South mix, and there’s optimism that C.J. Stroud could clear concussion protocol in time to start Sunday. If not, Davis Mills — who threw for 292 yards and two total touchdowns last week — has proven he can keep this offense humming.

Mills’ Week 10 performance was his best of the season, spreading the ball to Nico Collins (136 yards), Dalton Schultz (53 yards, TD), and Jayden Higgins (42 yards). Houston’s offensive line held up well against Jacksonville’s front, allowing only two sacks while paving the way for Woody Marks and Nick Chubb to combine for 110 yards on the ground. The balanced approach helped the Texans control tempo and clock, outgaining the Jaguars by over 100 yards.

The Titans, meanwhile, used the bye week to regroup after another frustrating close loss. Rookie quarterback Cam Ward continues to show flashes, completing 12 of 21 passes for 145 yards against the Chargers but taking four sacks and finishing with no touchdowns. Tony Pollard and Tyjae Spears split backfield work, but the run game again lacked consistency (88 total rushing yards). Tennessee’s defense kept the game close, holding Justin Herbert to 250 yards passing, but their inability to finish drives on either side remains the story of the season.

The biggest mismatch on paper lies up front. Houston’s defensive line has quietly improved — generating five sacks over the past two games — while Tennessee’s offensive line ranks near the bottom in protection metrics. If Mills starts again, expect Houston to lean on quick reads and play-action, exploiting the Titans’ soft middle coverage. Should Stroud return, the Texans’ vertical game could stretch Tennessee beyond its limits.

Houston Texans vs. Tennessee Titans Predictions

• Spread: Texans −7.5 (−115) — Houston’s offense is far more dynamic right now, and Tennessee’s post-bye adjustments may not be enough to slow down Collins and Schultz.
• Total: Under 39.5 (−110) — Tennessee’s offense remains limited, and Houston’s defense has allowed only 20.6 points per game at home. Expect a slower, more controlled pace.
• Moneyline: Texans (−375) — Whether it’s Mills or Stroud under center, Houston should maintain momentum against a Titans team that’s struggled to move the ball all season.

Bet: Texans ML (−375), Texans −7.5 (−115), Under 39.5 (−110)

Green Bay Packers vs. New York Giants Odds

The New York Giants head to Lambeau after a 24–20 loss in Chicago, while the Green Bay Packers return home off a defensive slugfest that ended 10–7 against Philadelphia. Green Bay’s defense set the tone last week by holding the Eagles to 183 passing yards and 111 rushing yards, limiting explosive plays and winning on money downs. That profile matches the market’s view of this matchup: Packers favored by more than a touchdown with a modest total.

New York’s offense showed real juice in Chicago. Jaxson Dart threw for 262 yards and added 66 rushing yards with two touchdowns, and the ground game produced 169 yards at 5.6 per carry behind Tyrone Tracy Jr.’s 71 yards. The flip side: pass protection was leaky (four sacks for 25 yards), and that volatility showed up late as drives stalled just outside scoring range. If the Giants replicate the run efficiency while trimming the negative plays, they can shorten the game.

Green Bay’s offense leaned on balance in the win at Philly. Jordan Love completed 20 of 36 for 176 yards, and Josh Jacobs carried 21 times for 74 yards and a touchdown. Targets were spread around — Christian Watson (45 yards) and Dontayvion Wicks (38) led the receivers — but the Packers still absorbed three sacks and didn’t find a passing touchdown. The approach was deliberate: work the run, avoid giveaways, and let the defense do the heavy lifting.

Stylistically, this sets up as a possession game. The Giants have the quarterback run element with Dart plus a productive Tracy Jr., but protection stress travels, and Green Bay’s front just forced three sacks and held the Eagles to seven points. If the Packers again control early downs with Jacobs and keep Love out of long yardage, their defense should dictate field position and tilt the fourth quarter.

New York Giants vs. Green Bay Packers Predictions

• Spread: Packers −7.5 (−110) — Green Bay’s defense is trending up and just held Philadelphia to seven; New York’s sack issues are a poor matchup on the road.
• Total: Under 44.5 (−110) — Both teams favored the run last week and played slower, lower-variance scripts; red-zone trips figure to be limited.
• Moneyline: Packers (−410) — The combination of home field, a steady run game, and a surging defense makes the upset unlikely.

Bet: Packers ML (−410), Packers −7.5 (−110), Under 44.5 (−110)

Chicago Bears vs. Minnesota Vikings Odds

The Chicago Bears and Minnesota Vikings meet again in a key NFC matchup, with both teams trending in opposite directions. Chicago is heating up after three straight wins, while Minnesota continues to slide, now sitting at 4–5 after dropping another home game. The first meeting between these two teams was tight, and both sides appear evenly matched entering Week 11.

Chicago leaned on its ground game to beat the Giants 24–20 last week. Caleb Williams threw for 220 yards and a touchdown while adding 63 rushing yards and another score. D’Andre Swift set the tone on the ground with 80 yards on 13 carries, and rookie Rome Odunze was once again the go-to receiver, hauling in six passes for 86 yards. The Bears controlled the line of scrimmage, finishing with 171 rushing yards as a team and zero sacks allowed — a huge turnaround from earlier in the year.

Minnesota’s 27–19 loss to Baltimore followed a similar pattern to their other recent defeats. J.J. McCarthy had a decent stat line (248 yards, one touchdown, two interceptions) but struggled against pressure and couldn’t sustain drives in the second half. The bright spot was the running game — the Vikings ran for 120 yards, with Aaron Jones Sr. and Jordan Mason combining for 72. Still, defensive lapses and turnovers again cost them, as Baltimore outgained them by 100 yards and dictated pace.

This game could come down to which defense holds up better against mobile quarterbacks. Williams has become more confident extending plays, while McCarthy’s improvisation has led to both highlights and mistakes. The Bears’ pass rush has been inconsistent, but their run defense has stiffened, allowing just 3.9 yards per carry over the past three weeks. If Chicago’s front can force McCarthy into third-and-longs and keep the ball in Williams’ hands, they have a clear path to another divisional win.

Chicago Bears vs. Minnesota Vikings Predictions

• Spread: Bears −3 (−118) — Chicago’s offense has found rhythm behind Caleb Williams, and the Vikings have dropped three straight while failing to score more than 20 in each.
• Total: Over 48.5 (−120) — Both defenses are middle of the pack, and Chicago’s offense has topped 24 points in back-to-back games.
• Moneyline: Bears (−166) — The Bears are playing their best football of the season and have the more dynamic quarterback.

Bet: Bears ML (−166), Bears −3 (−118), Over 48.5 (−120)

Cincinnati Bengals vs. Pittsburgh Steelers Odds

The Pittsburgh Steelers look to bounce back from a 25–10 loss to the Chargers, while the Cincinnati Bengals return from their bye hoping veteran Joe Flacco can keep the offense afloat until Joe Burrow’s expected Thanksgiving return. These AFC North rivals met earlier in the season, and Pittsburgh’s defense controlled that one with pressure and coverage discipline — a formula they’ll aim to repeat Sunday.

Pittsburgh’s offense has been inconsistent under Aaron Rodgers, who threw for just 161 yards and two interceptions last week. The Steelers managed only 73 rushing yards, with Jaylen Warren contributing 70 of them on 14 carries, and failed to convert key red-zone chances. The passing attack remained disjointed; Roman Wilson and DK Metcalf each caught two passes for 35 yards, while tight end Pat Freiermuth added 33. Rodgers took three sacks behind a struggling offensive line, and turnovers again dictated the outcome.

Cincinnati, meanwhile, enters rested but still dependent on Flacco, who put up monster volume in Week 9’s 47–42 shootout loss to Chicago — 470 yards, four touchdowns, and two interceptions. The Bengals relied heavily on their wideouts, with Tee Higgins (121 yards, 2 TDs) and Ja’Marr Chase (111 yards) each topping the century mark. The run game was nearly nonexistent, totaling just 46 yards, though the bye week may have given the offensive line a chance to regroup. The defense, however, remains a concern, having surrendered 283 rushing yards to the Bears before the break.

This matchup pits a Steelers front seven capable of generating havoc against a Bengals offense that leans entirely on Flacco’s arm. If Pittsburgh’s pass rush can collapse the pocket — as it did against Justin Herbert (five sacks) — it could force turnovers and short fields. For Cincinnati, the formula is clear: protect Flacco, get Chase and Higgins in space, and hope the defense can contain Warren and Metcalf enough to stay in a one-score game.

Pittsburgh Steelers vs. Cincinnati Bengals Predictions

• Spread: Bengals +6.5 (−115) — Cincinnati’s rested and still explosive through the air, while Pittsburgh’s offense remains unreliable on the road.
• Total: Under 49.5 (−110) — Both defenses are better than the scoreboard suggests; if the Bengals’ line tightens up post-bye, scoring could slow considerably.
• Moneyline: Steelers (−225) — Pittsburgh’s defense should create just enough short fields to edge a tight, low-possession contest.

Bet: Steelers ML (−225), Bengals +6.5 (−115), Under 49.5 (−110)

Carolina Panthers vs. Atlanta Falcons Odds

The Carolina Panthers are licking their wounds after a 17–7 loss to the Saints, while the Atlanta Falcons fly back stateside following a 31–25 overtime defeat in Berlin. Atlanta’s offense flashed in spots overseas: Michael Penix Jr. threw for 177 yards with a touchdown, and the ground game produced 140 yards behind Bijan Robinson (17 for 84) and Tyler Allgeier (11 for 57). Drake London was the featured target (6 for 104 and a score), but three sacks and a lost fumble stalled late drives.

The bigger concern for Atlanta was run defense. Indianapolis piled up 323 rushing yards, with Jonathan Taylor ripping off 244 and three touchdowns. That stress spilled into the pass rush, where Penix Jr. was sacked three times and pressured into quick throws. Even with London winning on the perimeter and Kyle Pitts adding 38 yards, Atlanta’s negative plays and explosives allowed swung the game in overtime.

Carolina’s offense couldn’t sustain drives against New Orleans. Bryce Young completed 17 of 25 for 124 yards with an interception and two sacks, and the Panthers’ lone touchdown came on the ground from Rico Dowdle (18 for 53). The passing game leaned on Tetairoa McMillan (5 for 60) and Ja’Tavion Sanders (5 for 32), but chunk gains were rare and third downs proved costly. Defensively, Carolina ceded 282 passing yards and two scores yet held the Saints to 122 rushing yards, keeping the game within reach into the fourth quarter.

Matchup-wise, Atlanta’s rushing duo vs. Carolina’s front is pivotal. If the Falcons recreate the Robinson/Allgeier efficiency from Berlin and limit giveaways (one lost fumble last week), they can play from ahead and set up play-action shots to London. Carolina’s path is a lower-variance script: lean on Dowdle, shorten possessions, and force Atlanta to drive the field. Given recent results, a tighter, lower-scoring game is very live.

Carolina Panthers vs. Atlanta Falcons Predictions

• Spread: Panthers +3.5 (−105) — Atlanta’s run defense just allowed 323 yards, and Carolina has shown it can muddy games with clock control.
• Total: Under 42.5 (−104) — Both offenses skew run-heavy and recently struggled to finish drives; explosives should be limited.
• Moneyline: Falcons (−180) — Atlanta’s higher ceiling with Drake London and Bijan Robinson plus the return from Berlin should be enough at home.

Bet: Falcons ML (−180), Panthers +3.5 (−110), Under 42.5 (−104)

Los Angeles Chargers vs. Jacksonville Jaguars Odds

The Los Angeles Chargers visit the Jacksonville Jaguars in a matchup featuring two playoff hopefuls trying to stabilize midseason inconsistency. Both teams have shown flashes of high-end offense mixed with stretches of inefficiency. Los Angeles beat Pittsburgh 25–10 last week behind a strong defensive performance and a balanced attack, while Jacksonville fell 36–29 in Houston despite a solid day from Trevor Lawrence.

For the Chargers, Justin Herbert was sharp and efficient, completing 20 of 33 for 220 yards and a touchdown while spreading the ball to ten receivers. Ladd McConkey led with four grabs for 107 yards and a score, and Kimani Vidal handled 25 carries for 95 yards and a touchdown. The defense sacked Aaron Rodgers three times and held the Steelers under 200 total yards with two takeaways.

Jacksonville couldn’t slow Houston’s passing game. Davis Mills threw for 292 yards and two touchdowns, with Nico Collins posting 136 yards on seven catches. Lawrence finished 13-of-23 for 158 yards with one touchdown and one interception but took five sacks behind an overmatched offensive line. Travis Etienne added 58 yards and a score, but the defense allowed 130 rushing yards and 36 points overall.

The trench battle tilts toward Los Angeles’ pass rush against a Jacksonville line that has allowed frequent pressure the past three weeks. Herbert’s timing with McConkey and Quentin Johnston gives the Chargers reliable mid-range production, and Vidal’s emergence stabilizes the run game. For Jacksonville to flip it at home, they’ll need cleaner protection, a turnover-free game from Lawrence, and explosives from Etienne and Jakobi Meyers to punish blitz looks.

Los Angeles Chargers vs. Jacksonville Jaguars Predictions

• Spread: Chargers −3 (−102) — Protection concerns for Jacksonville persist, and Los Angeles matches up well with its front seven.
• Total: Over 43.5 (−110) — Both offenses can exploit secondary weaknesses; late-game pace could push this over.
• Moneyline: Chargers (−148) — The pass-rush edge and Herbert’s consistency give L.A. a narrow advantage.

Bet: Chargers ML (−148), Chargers −3 (−102), Over 43.5 (−110)

Seattle Seahawks vs. Los Angeles Rams Odds

The Seattle Seahawks and Los Angeles Rams meet in Week 11 in one of the most intriguing matchups of the season — and one loaded with subplots. Most notably, it’s Cooper Kupp’s return to Los Angeles after signing with Seattle this past offseason. The Rams are rolling after a 42–26 win over San Francisco, while the Seahawks dismantled Arizona 44–22 behind a dominant ground game and an efficient outing from Sam Darnold.

Darnold completed 10 of 12 passes for 178 yards and a touchdown, with Jaxon Smith-Njigba (5 for 93) and Kupp (2 for 74) leading a versatile receiving group. The run game was equally balanced — Zach Charbonnet and Kenneth Walker III combined for 150 rushing yards and two scores — and Seattle averaged nearly seven yards per play. Their offensive line, however, allowed four sacks, something to monitor against Los Angeles’ aggressive front.

The Rams, meanwhile, are starting to click at the perfect time. Matthew Stafford was brilliant in last week’s win, throwing for 280 yards and four touchdowns. Kyren Williams carried 14 times for 73 yards and two scores, and Puka Nacua and Davante Adams each topped 75 receiving yards. Los Angeles has now scored 84 points in the past two games and is finally healthy across its offensive core.

Defensively, both teams are opportunistic but vulnerable against big plays. Seattle’s secondary has given up 20+ yard gains at one of the highest rates in the NFC, while the Rams’ pass defense has been shredded by tempo offenses. Expect an aggressive script from both coaches — Sean McVay leveraging Nacua and Williams in motion-heavy looks, and the Seahawks countering with heavy play-action shots to Kupp and Smith-Njigba.

Seattle Seahawks vs. Los Angeles Rams Predictions

• Spread: Rams −2.5 (−120) — Los Angeles’ offense is hitting its stride, and Stafford should exploit Seattle’s secondary at home.
• Total: Over 48.5 (−110) — Both teams rank top-10 in yards per play and have elite red-zone finishers; fireworks are likely.
• Moneyline: Rams (−156) — McVay’s group has regained form, and Stafford’s chemistry with Nacua and Adams should carry them late.

Bet: Rams ML (−156), Rams −2.5 (−120), Over 48.5 (−110)

San Francisco 49ers vs. Arizona Cardinals Odds

The San Francisco 49ers and Arizona Cardinals clash in an NFC West rematch that could have major implications for both teams’ playoff outlooks. San Francisco bounced back from a rough stretch with a decisive 42–26 loss to the Rams, while Arizona continued its inconsistent run with a 44–22 defeat in Seattle. Both teams are trying to regain footing after divisional losses.

San Francisco’s offense produced through the air last week, but defensive breakdowns buried them early. Mac Jones completed 33 of 39 passes for 319 yards and three touchdowns, spreading the ball among nine different targets. George Kittle (9 for 84), Christian McCaffrey (8 for 66), and Jauan Jennings (6 for 71) all moved the chains consistently, but the defense allowed 42 points and nearly eight yards per pass attempt. The 49ers’ pass rush never hit home, recording zero sacks, and that’s an area they must fix entering this matchup.

Arizona’s struggles were more pronounced on defense. The Cardinals allowed 44 points and 198 rushing yards to Seattle, unable to contain Zach Charbonnet or Kenneth Walker III. Jacoby Brissett went 22-of-45 for 206 yards and two touchdowns but was sacked five times and fumbled twice. Tight end Trey McBride (9 for 127) continues to be the lone bright spot, while rookie back Emari Demercado added 95 scrimmage yards in limited work.

This shapes up as another uphill battle for Arizona. San Francisco’s offensive personnel matches up well against a Cardinals secondary that’s allowed the league’s highest completion rate over the past three weeks. With McCaffrey and Kittle creating mismatches underneath, the 49ers should have little trouble moving the ball. The key will be protecting Mac Jones — if the offensive line holds, San Francisco’s balance should carry them.

San Francisco 49ers vs. Arizona Cardinals Predictions

• Spread: 49ers -2.5 (-110) — San Francisco’s offensive versatility and Arizona’s defensive woes make this a solid number to lay on the road.
• Total: Over 48.5 (-115) — Both defenses have been giving up points in bunches, and with McBride emerging as a reliable option for Brissett, Arizona should contribute to the scoring.
• Moneyline: 49ers (-148) — San Francisco has too many weapons and should control the game flow even if Arizona starts fast.

Bet: 49ers ML (-148), 49ers -2.5 (−110), Over 48.5 (-115)

Baltimore Ravens vs. Cleveland Browns Odds

The Baltimore Ravens head to Cleveland after a 27–19 win in Minnesota, while the Cleveland Browns return home off a 27–20 loss to the Jets. Baltimore leaned on balance in Week 10: Lamar Jackson went 17/29 for 176 yards with one touchdown and one interception, and the backfield piled up 36 rushes for 152 yards, led by Derrick Henry’s 20 carries for 75 yards and Keaton Mitchell’s 31 yards on just four attempts. Baltimore’s pass game spread the ball around, with Zay Flowers topping the team at 75 yards and Charlie Kolar adding a 23-yard grab.

That formula matches a clear weak spot Cleveland showed last week. The Browns allowed the Jets to rush for 127 yards (Breece Hall had 21 carries for 83) and also surrendered a 42-yard receiving touchdown to Hall on New York’s lone catch by a running back. If Baltimore again marries Jackson’s efficiency with volume on the ground, the Browns’ front that faced 33 Jets rushing attempts could see another heavy dose on Sunday.

Offensively, Cleveland will try to stabilize after a choppy outing. Dillon Gabriel finished 17/32 for 167 yards with two touchdowns but also two interceptions, while Quinshon Judkins handled 22 carries for 75 yards. The Browns did create explosives at receiver—Jerry Jeudy posted 6/78/1 and Harold Fannin Jr. added 4/44—but sustaining drives was an issue as the offense averaged 4.9 yards per rush and 5.2 yards per pass attempt. That meets a Ravens defense that just held Minnesota to 19 points and 120 rushing yards; despite J.J. McCarthy throwing for 248 yards, Baltimore limited explosive runs (no Viking topped 48 rushing yards) and won the situational downs.

On paper, this shapes up like a field-position game where Baltimore’s ground volume and red-zone mix of Henry/Jackson could be the separator, while Cleveland likely needs another efficient day from Jeudy and David Njoku to keep pace. Given last week’s box scores—Ravens thriving with 36 team rushes and the Browns allowing 30+ rush attempts—the run game and defense may drive the script more than splashy downfield shots.

Baltimore Ravens vs. Cleveland Browns Predictions

• Spread: Ravens -8.5 (-105) — Baltimore’s rushing balance and defensive edge should control the tempo against a struggling Cleveland offense.
• Total: Under 40.5 (-110) — Both teams lean on the run and play slow, with Cleveland’s pass game unlikely to test Baltimore deep.
• Moneyline: Ravens (-470) — The Browns’ line issues and limited vertical attack make an upset at home unlikely.

Bet: Ravens ML (-470), Ravens -8.5 (-105), Under 40.5 (-110)

Kansas City Chiefs vs. Denver Broncos Odds

The 5–4 Kansas City Chiefs roll into Denver off their bye, while the 8–2 Denver Broncos are fresh from a 10–7 Thursday win over the Raiders. Kansas City’s most recent outing was a 28–21 loss to Buffalo in which the offense sputtered: 226 passing yards on 35 attempts with just one touchdown, and a run game that never found rhythm. Denver, meanwhile, leaned on defense and field position to grind past Las Vegas, holding the Raiders to 143 passing yards and 74 rushing yards.

Stylistically, this sets up as a tempo edge for Kansas City. Denver’s pass rush has been feisty, but the Broncos still rank near the league’s basement in yards per play allowed and haven’t pressured opposing quarterbacks at an elite rate. Even in the loss to Buffalo, Kansas City created explosives on the perimeter and can get more out of its vertical shots after a full week to self-scout. The bye should also help the Chiefs clean up red-zone sequencing and short-yardage inefficiency that stalled drives in Week 10.

On the other side, Denver’s offense continues to live on the ground and quick-game. J.K. Dobbins and the committee combined for 84 rushing yards on 27 attempts against the Raiders, but explosive plays were scarce and the passing game posted 150 yards at 5.4 per attempt. That conservative profile meets a Kansas City defense that has quietly been stingy versus both run and pass this season, allowing chunk gains infrequently and closing drives with sacks and negative plays. If the Broncos fall behind schedule, they’ll struggle to keep up in long down-and-distance.

Add in the rest advantage and matchup leverage for Kansas City’s front, and the path tilts toward a road cover in a lower-variance game. Expect the Chiefs to lean into early down passing, mix in play-action shots, and let their defense squeeze Denver into a field-position slog. The market total still sits in the mid-40s; with both teams’ recent tendencies, that number is a touch high.

Kansas City Chiefs vs. Denver Broncos Predictions

• Spread: Chiefs -3.5 (-110) — Kansas City’s post-bye script and defensive edge should be enough to separate against a conservative Denver offense.
• Total: Under 43.5 (-110) — Both teams trend toward shorter games and slower pace; Denver’s red-zone profile keeps points modest.
• Moneyline: Chiefs (-185) — Better quarterback play and situational defense give the visitors the higher floor.

Bet: Chiefs ML (–195), Chiefs –3.5 (–110), Under 43.5 (–110)

Detroit Lions vs. Philadelphia Eagles Odds

The Philadelphia Eagles edged Green Bay 10–7 on the road last week, grinding through a defensive slugfest where Jalen Hurts threw for 183 yards with one touchdown while adding 27 rushing yards. Saquon Barkley handled 22 carries for 60 yards, and DeVonta Smith led all receivers with 69 yards and a score. Despite modest yardage totals, the Eagles controlled possession and limited the Packers to 176 passing yards and 104 on the ground, reinforcing their identity as a team built on balance and defensive control.

The Detroit Lions, meanwhile, dismantled Washington 44–22 behind a clean performance from Jared Goff, who completed 25 of 33 passes for 320 yards and three touchdowns. The backfield was dominant: Jahmyr Gibbs ripped off 142 yards and two scores on just 15 carries, and David Montgomery added 71 yards on another 15 attempts. With 546 total yards of offense and zero sacks allowed, the Lions looked like a fully operational unit entering this road test.

This matchup pits two of the NFC’s most physical teams in a likely playoff preview. Philadelphia’s front seven will aim to disrupt Detroit’s rhythm early, forcing Goff to adjust under pressure rather than sit comfortably behind a clean pocket as he did in Washington. However, the Lions’ offensive line has protected well, and Gibbs’ burst gives them an explosive counter to the Eagles’ pass rush. On the other side, Hurts and Barkley face a Lions defense that surrendered 93 rushing yards to the Commanders but continues to limit yards per carry and explosive plays.

The Eagles’ ability to win ugly remains their calling card, but Detroit enters with a hotter offense and more rest after playing earlier in the week. If Goff maintains efficiency and the backfield duo stays balanced, the Lions have enough firepower to challenge Philadelphia’s coverage-heavy scheme and steal a statement win on the road.

Detroit Lions vs. Philadelphia Eagles Predictions

• Spread: Lions +2.5 (−105) — Detroit’s offensive rhythm and backfield depth make this line appealing against a Philly team that leaned heavily on defense to escape Green Bay.
• Total: Under 47.5 (−118) — Both defenses rank among the most disciplined units in the NFC, and the Eagles’ slow offensive pace points toward a grind-it-out contest.
• Moneyline: Lions (+120) — Detroit’s balance on offense and superior recent form offer slight upset value.

Bet: Lions ML (+120), Lions +2.5 (−105), Under 47.5 (−118)

Dallas Cowboys vs. Las Vegas Raiders Odds

The Week 11 slate wraps up with a non-conference tilt between the Dallas Cowboys and Las Vegas Raiders on Monday Night Football. Dallas is fresh off a bye and draws a Raiders team that managed just 7 points in last week’s loss to Denver.

Dallas’ most recent box score (vs. Arizona) still brings plenty of optimism despite the defeat. Dak Prescott went 24/39 for 250 yards with a touchdown and an interception, and the passing game fed CeeDee Lamb (7 receptions, 85 yards) and Jake Ferguson (5 for 50). On the ground, Dallas produced 123 rushing yards, paced by Javonte Williams’ 15 carries for 83 yards, while KaVontae Turpin and Malik Davis chipped in. Coming out of the bye, that balanced profile matches up well with a Raiders defense that just spent four quarters in a slugfest.

Las Vegas, meanwhile, simply didn’t move the ball in Denver: Geno Smith finished 16/26 for 143 yards with a pick, and the run game totaled 74 yards (Ashton Jeanty 19-60). Tyler Lockett (5-44) and Brock Bowers (31-yard long) supplied the only real chunk plays. That limited explosiveness is a tough fit if Dallas plays with a lead and forces Smith into longer passing downs.

One more data point for the total: that Raiders-Broncos game produced just 17 combined points, and Las Vegas has leaned on shorter, clock-draining touches (Tre Tucker 2-28 receiving; Jeanty 19 carries). If Dallas leans into its post-bye ground game again behind Williams and Prescott’s keepers, possessions can stay modest.

Dallas Cowboys vs. Las Vegas Raiders Predictions

• Spread: Cowboys -3.5 (-110) — Dallas comes in rested and has the clearer offensive ceiling after posting 250 passing yards and 123 rushing yards in its last outing, while Las Vegas managed only 143 passing yards and 74 rushing yards against Denver.
• Total: Under 50.5 (–110) — Las Vegas’ 7-point showing last week plus a preference for run-rate on both sides (Williams 15 carries; Jeanty 19) point to fewer possessions than this number implies.
• Moneyline: Cowboys (-192) — With the bye advantage and more reliable pass-catchers (Lamb, Ferguson), Dallas is the safer side to close out MNF.

Bet: Cowboys ML (-192), Cowboys -3.5 (-110), Under 50.5 (-110)

NFL Week 11 Best Bets

Check out our best NFL bets for Week 11:

• Baltimore Ravens -8.5 at Cleveland Browns (-105)
• Kansas City Chiefs -3.5 at Denver Broncos (-110)
• Detroit Lions +2.5 at Philadelphia Eagles (-105)

Baltimore has found rhythm behind a 3-game winning streak, and their Week 10 box score backed up the dominance. Lamar Jackson led an offense that produced 152 rushing yards on 36 carries while limiting Minnesota to 19 points. Cleveland’s offensive line has allowed heavy pressure and ranks near the bottom of the league in sacks allowed — a bad formula against a Ravens front that just won at the line against J.J. McCarthy and company. Baltimore’s rushing volume and red-zone edge make them the side to trust again.

Kansas City gets a Denver team that just managed 10 points in a Thursday win over Las Vegas. Patrick Mahomes and company are coming off their bye and should benefit from a cleaner game plan after averaging 226 passing yards against Buffalo despite inefficiency in key spots. Denver’s defense has been stout but bendable; its run fits have shown holes against patient offenses, and Kansas City’s short-passing rhythm should exploit that.

Detroit remains an undervalued underdog. Jared Goff threw for 320 yards and 3 touchdowns in Washington, and the backfield tandem of Jahmyr Gibbs (142 yards, 2 TDs) and David Montgomery (71 yards) is giving defenses problems. Philadelphia is coming off a 10–7 grinder where Jalen Hurts threw for just 183 yards, and Saquon Barkley averaged 2.7 yards per carry. Detroit’s offense has been sharper, more balanced, and explosive enough to cover or win outright.

If you roll these three into a parlay at approximate prices of -105, -110, and -105, the combined odds land around +595. A $100 wager would return roughly $695 total ($595 profit).

For more parlay bets, check out our best NFL parlays for each week. For the NCAAF fans, we also have some enticing College Football parlays of the week.